Evidence map›Paper›PMID 31520092›Full record

ArticleOperative Orthopadie und Traumatologie2019

[Fast track concepts in total knee arthroplasty: use of tranexamic acid and local intra-articular anesthesia technique].

Wolf Petersen, Sebastian Bierke, Tillmann Hees, Katrin Karpinski, Martin Häner

Abstract read
PubMed Publisher
In one paragraph

Article in Operative Orthopadie und Traumatologie, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Wolf PetersenKlinik für Orthopädie und Unfallchirurgie, Martin-Luther-Krankenhaus, Berlin Grunewald, Caspar-Theyss-Straße 27-31, 14193, Berlin, Deutschland. wolf.petersen@pgdiakonie.de.
Sebastian BierkeKlinik für Orthopädie und Unfallchirurgie, Martin-Luther-Krankenhaus, Berlin Grunewald, Caspar-Theyss-Straße 27-31, 14193, Berlin, Deutschland.
Tillmann HeesKlinik für Orthopädie und Unfallchirurgie, Martin-Luther-Krankenhaus, Berlin Grunewald, Caspar-Theyss-Straße 27-31, 14193, Berlin, Deutschland.
Katrin KarpinskiKlinik für Orthopädie und Unfallchirurgie, Martin-Luther-Krankenhaus, Berlin Grunewald, Caspar-Theyss-Straße 27-31, 14193, Berlin, Deutschland.
Martin HänerKlinik für Orthopädie und Unfallchirurgie, Martin-Luther-Krankenhaus, Berlin Grunewald, Caspar-Theyss-Straße 27-31, 14193, Berlin, Deutschland.
Martin-Luther-Krankenhaus · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveFast track concepts are used to reduce the risk of perioperative and postoperative complications after total knee arthroplasty. INDICATIONS: The described concepts are used for patients with indications for the implantation of a total knee prosthesis. CONTRAINDICATIONS: Contraindications for fast track concepts are aged patients, dementia, American Society of Anesthesiologists (ASA) grade IV and implantation of large revision or tumor prostheses. Contraindications for tranexamic acid are bleeding in the urinary tract, caution in cases of known epilepsy, individual risk assessment in existing thromboses or increased thrombosis risk, fresh myocardial infarction, conditions following fresh pulmonary embolism, percutaneous transluminal coronary angioplasty (PTCA) and stent implantation. Contraindications for ropivacaine are hypersensitivity (allergy) to ropivacaine and other amide type topical anesthetics and hypovolemia. SURGICAL TECHNIQUE: Preoperative administration of 1 g tranexamic acid and intraoperative local infiltration anesthesia are carried out. After femoral and tibial bone resection and before cementing the femoral and tibial components, approximately 40 ml of ropivacaine (2%) is injected into the posterior capsule. This is followed by injection of the medial and lateral collateral ligaments with approximately 20 ml each and infiltration of Hoffa's fat pad and the extensor apparatus also with approximately 20 ml local anesthetic. After cementing, the subcutaneous tissue is infiltrated with approximately 50 ml ropivacaine solution. POSTOPERATIVE MANAGEMENT: On the same day as the operation the patient is mobilized with the help of a physiotherapist. The patient should, if possible, walk a few steps on crutches. Systemic analgesic treatment is carried out according to the World Health Organization (WHO) staged scheme II with a weak opioid and first stage non-opioid analgesic (nonsteroidal anti-inflammatory drug, NSAID and/or metamizole). Gabapentin can be used as an adjuvant comedication. Medicinal thrombosis prophylaxis is carried out with a low molecular weight heparin for 2 weeks postoperatively.

resultsIn 100 patients who preoperatively received 1 g tranexamic acid and intra-articular infiltration anesthesia, in the evening of the day of the operation the pain was on average 2.1 (±1.8) on the numeric pain rating scale (NPRS). In one patient, there was a sensitive deficit of the lower leg and foot. A motor deficit was not observed. A total of 90 patients were able to raise and straighten leg. On the day of surgery 68 patients were able to walk more than 10 steps and 22 patients could be mobilized to a standing position. The mean length of hospital stay was 6.6 days (5-11 days). No infections, thromboses or pulmonary embolisms occurred.

Indexed as

Anesthesia, LocalAnesthetics, LocalArthroplasty, Replacement, KneeHumansTranexamic AcidTreatment OutcomeAnesthetics, LocalTranexamic AcidAnesthesia, conductionLength of stayLocal anesthesiaRopivacaineTranexamic acid

Identifiers

PMID31520092
OpenAlexW2972369664

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.