Evidence map›Paper›PMID 31520073›Full record

ReviewNature reviews. Molecular cell biology2019

Reading, writing and erasing mRNA methylation.

Sara Zaccara, Ryan J Ries, Samie R Jaffrey

Erratum issued Registry-linked trialAbstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Molecular cell biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT04533282 (Epitranscriptomic Biomarkers for Ischemic Heart Disease), which is not on this map. Cited by 1,542 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1,542citing papers in PubMed, 1 pooled it
101.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04533282 unknown statusnot on this mapstarted 2020, after this paper: background citation

Epitranscriptomic Biomarkers for Ischemic Heart Disease (IHD-EPITRAN) - A Prospective Cohort Study

Typeobservational_patient_registrySponsorHospital District of Helsinki and UusimaaRan2020 to 2025Enrolled200ConditionsIschemic Heart Disease, Coronary Artery Disease, Aortic Valve Stenosis, Acute Myocardial InfarctionArmsBlood samples., Collection of right atrial appendage tissue sample., Health Survey, Clinical symptom scaling, Transthoracic echocardiography (TTE)
3 · Its place in the literature

Who cites it

1,542 citing papers in PubMed, 1 synthesis or guideline pooled it, 2,691 citations in OpenAlex.

  1. Pooled it
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  20. mNature metabolism · 2026
    Article

1,482 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Sara ZaccaraDepartment of Pharmacology, Weill Medical College, Cornell University, New York, NY, USA.ORCID http://orcid.org/0000-0002-6569-2015
Ryan J RiesDepartment of Pharmacology, Weill Medical College, Cornell University, New York, NY, USA.
Samie R JaffreyDepartment of Pharmacology, Weill Medical College, Cornell University, New York, NY, USA. srj2003@med.cornell.edu.ORCID http://orcid.org/0000-0003-3615-6958
Cornell University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

RNA methylation to form N

Indexed as

Gene Expression Regulation, NeoplasticRNA Processing, Post-TranscriptionalAdenosineAnimalsHumansMethylationNeoplasmsRNA, MessengerRNA, NeoplasmAdenosineN-methyladenosineRNA, MessengerRNA, Neoplasm

Identifiers

PMID31520073
OpenAlexW2972933339

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.