Evidence map›Paper›PMID 31520065›Full record

ArticleScientific reports2019

Blood pressure change across pregnancy in white British and Pakistani women: analysis of data from the Born in Bradford cohort.

Diane Farrar, Gillian Santorelli, Debbie A Lawlor, Derek Tuffnell, Trevor A Sheldon, Jane West, Corrie Macdonald-Wallis

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 23 citations in OpenAlex.

  1. Trial
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Diane FarrarBradford Institute for Health Research, Bradford Royal Infirmary, Bradford, UK. diane.farrar@bthft.nhs.uk.ORCID http://orcid.org/0000-0002-5625-761X
Gillian SantorelliBradford Institute for Health Research, Bradford Royal Infirmary, Bradford, UK.ORCID http://orcid.org/0000-0003-0427-1783
Debbie A LawlorMRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.
Derek TuffnellBradford Women's and Newborn Unit, Bradford, UK.
Trevor A SheldonDepartment of Health Sciences, University of York, York, UK.
Jane WestBradford Institute for Health Research, Bradford Royal Infirmary, Bradford, UK.ORCID http://orcid.org/0000-0002-5770-8363
Corrie Macdonald-WallisCentre for Exercise, Nutrition and Health Sciences, University of Bristol, Bristol, UK.
Bradford Royal Infirmary · GBNational Institute for Health Research · GBUniversity of Bristol · GBUniversity of York · GB

Funding

Metabolomic and Epigenomic Mechanisms in Developmental Overnutrition.R01DK103246 · NIDDK · UNIVERSITY OF BRISTOL · PI LAWLOR, DEBORAH ANNE · 2014 to 2018
$2.2M
British Heart Foundation AA/18/7/34219British Heart Foundation CS/16/4/32482Department of Health NF-SI-0611-10196Department of Health PDF-2014-07-019Medical Research Council G0601712Medical Research Council MC_UU_00011/6Medical Research Council MR/K021656/1Medical Research Council MR/N024397/1NIDDK NIH HHS R01 DK103246Wellcome TrustWellcome Trust WT101597MAWellcome Trust WT10159MA
6 · The paper itself

Abstract

The incidence of gestational hypertension (GH) and pre-eclampsia (PE) is increasing. Use of blood pressure (BP) change patterns may improve early detection of BP abnormalities. We used Linear spline random-effects models to estimate BP patterns across pregnancy for white British and Pakistani women. Pakistani women compared to white British women had lower BP during the first two trimesters of pregnancy, irrespective of the development of GH or PE or presence of a risk factor. Pakistani compared to white British women with GH and PE showed steeper BP increases towards the end of pregnancy. Pakistani women were half as likely to develop GH, but as likely to develop PE than white British women. To conclude; BP trajectories differ by ethnicity. Because GH developed evenly from 20 weeks gestation, and PE occurred more commonly after 36 weeks in both ethnic groups, the lower BP up to the third trimester in Pakistani women resulted in a lower GH rate, whereas PE rates, influenced by the steep third trimester BP increase were similar. Criteria for diagnosing GH and PE may benefit from considering ethnic differences in BP change across pregnancy.

Indexed as

AdultBlood PressureBody Mass IndexCohort StudiesFemaleHumansHypertension, Pregnancy-InducedIncidenceMaternal AgePakistanPre-EclampsiaPregnancyUnited Kingdom

Identifiers

PMID31520065
PMCPMC6744423
OpenAlexW2972508131

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.