ArticleNature communications2019
EMS1 and BRI1 control separate biological processes via extracellular domain diversity and intracellular domain conservation.
Article in Nature communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed, 63 citations in OpenAlex.
- Ecological Adaptation Mechanisms Underlying Successful Plant Reproduction.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- Creation of thermosensitive male sterility line in rice via a temperature-sensitive mutation in receptor kinase.Plant biotechnology journal · 2025Article
- Dressed Up to the Nines: The Interplay of Phytohormones Signaling and Redox Metabolism During Plant Response to Drought.Plants (Basel, Switzerland) · 2025Review
- Sex on Steroids: How Brassinosteroids Shape Reproductive Development in Flowering Plants.Plant & cell physiology · 2024Review
- Differential phosphorylation of Ca2+-permeable channel CYCLIC NUCLEOTIDE-GATED CHANNEL20 modulates calcium-mediated freezing tolerance in Arabidopsis.The Plant cell · 2024Article
- Brassinosteroid biosynthesis and signaling: Conserved and diversified functions of core genes across multiple plant species.Plant communications · 2024Review
- MS2/GmAMS1 encodes a bHLH transcription factor important for tapetum degeneration in soybean.Plant cell reports · 2024Article
- Interaction of the Transcription Factors BES1/BZR1 in Plant Growth and Stress Response.International journal of molecular sciences · 2024Review
- An update on evolutionary, structural, and functional studies of receptor-like kinases in plants.Frontiers in plant science · 2024Review
- Asymmetric Evolution of Protein Domains in the Leucine-Rich Repeat Receptor-Like Kinase Family of Plant Signaling Proteins.Molecular biology and evolution · 2023Article
- Kinase regulators evolved into two families by gain and loss of ability to bind plant steroid receptors.Plant physiology · 2023Article
- Advances in Receptor-like Protein Kinases in Balancing Plant Growth and Stress Responses.Plants (Basel, Switzerland) · 2023Review
- Grain Disarticulation in Wild Wheat and Barley.Plant & cell physiology · 2022Article
- BES1/BZR1 Family Transcription Factors Regulate Plant Development via Brassinosteroid-Dependent and Independent Pathways.International journal of molecular sciences · 2022Review
- The genome of homosporous maidenhair fern sheds light on the euphyllophyte evolution and defences.Nature plants · 2022Article
- Evolutionary Analysis and Functional Identification of Ancient Brassinosteroid Receptors inInternational journal of molecular sciences · 2022Article
- Engineering Chimeras by Fusing Plant Receptor-like Kinase EMS1 and BRI1 Reveals the Two Receptors' Structural Specificity and Molecular Mechanisms.International journal of molecular sciences · 2022Article
- Receptor-like protein kinases in plant reproduction: Current understanding and future perspectives.Plant communications · 2022Review
- Phytohormone biosynthesis and signaling pathways of mosses.Plant molecular biology · 2021Review
- Insight into early diversification of leucine-rich repeat receptor-like kinases provided by the sequenced moss and hornwort genomes.Plant molecular biology · 2021Article
Corrections and comments
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In flowering plants, EMS1 (Excess Microsporocytes 1) perceives TPD1 (Tapetum Determinant 1) to specify tapeta, the last somatic cell layer nurturing pollen development. However, the signaling components downstream of EMS1 are relatively unknown. Here, we use a molecular complementation approach to investigate the downstream components in EMS1 signaling. We show that the EMS1 intracellular domain is functionally interchangeable with that of the brassinosteroid receptor BRI1 (Brassinosteroid Insensitive 1). Furthermore, expressing EMS1 together with TPD1 in the BRI1 expression domain could partially rescue bri1 phenotypes, and led to the dephosphorylation of BES1, a hallmark of active BRI1 signaling. Conversely, expressing BRI1 in the EMS1 expression domain could partially rescue ems1 phenotypes. We further show that PpEMS1 and PpTPD1 from the early land plant Physcomitrella patens could completely rescue ems1 and tpd1 phenotypes, respectively. We propose that EMS1 and BRI1 have evolved distinct extracellular domains to control different biological processes but can act via a common intracellular signaling pathway.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.