Evidence map›Paper›PMID 31519810›Full record

ArticleJournal of cell science2019

Mechanical stress induces a scalable switch in cortical flow polarization during cytokinesis.

Deepika Singh, Devang Odedra, Priyanka Dutta, Christian Pohl

Open access · hybridAbstract read
In one paragraph

Article in Journal of cell science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. A cytokinetic ring-driven cell rotation achieves Hertwig's rule in early development.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  7. Article
  8. OSGN-1 is a conserved flavin-containing monooxygenase required to stabilize the intercellular bridge in late cytokinesis.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. CYK-1/Formin activation in cortical RhoA signaling centers promotes organismal left-right symmetry breaking.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  15. Article
  16. Going with the flow: insights fromPhilosophical transactions of the Royal Society of London. Series B, Biological sciences · 2020
    Review
  17. Article
  18. Article
  19. Roles of Actin in the Morphogenesis of the EarlyInternational journal of molecular sciences · 2020
    Review
  20. The Unusual Suspects in Cytokinesis: Fitting the Pieces Together.Frontiers in cell and developmental biology · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Deepika SinghBuchmann Institute for Molecular Life Sciences and Institute of Biochemistry II, Medical Faculty, Goethe University, Max-von-Laue-Strasse 15, 60438 Frankfurt (Main), Germany.ORCID 0000-0001-5635-5458
Devang OdedraBuchmann Institute for Molecular Life Sciences and Institute of Biochemistry II, Medical Faculty, Goethe University, Max-von-Laue-Strasse 15, 60438 Frankfurt (Main), Germany.ORCID 0000-0002-9534-9234
Priyanka DuttaBuchmann Institute for Molecular Life Sciences and Institute of Biochemistry II, Medical Faculty, Goethe University, Max-von-Laue-Strasse 15, 60438 Frankfurt (Main), Germany.ORCID 0000-0002-6391-3873
Christian PohlBuchmann Institute for Molecular Life Sciences and Institute of Biochemistry II, Medical Faculty, Goethe University, Max-von-Laue-Strasse 15, 60438 Frankfurt (Main), Germany pohl@em.uni-frankfurt.de.ORCID 0000-0002-9591-482X
Goethe University Frankfurt · DE

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Ann E. Rougvie · 2012 to 2026
$7.5M
NIH HHS P40 OD010440
6 · The paper itself

Abstract

During animal development, cells need to sense and adapt to mechanical forces from their environment. Ultimately, these forces are transduced through the actomyosin cortex. How the cortex simultaneously responds to and creates forces during cytokinesis is not well understood. Here we show that, under mechanical stress, cortical actomyosin flow can switch polarization during cytokinesis in the

Indexed as

Stress, MechanicalActin CytoskeletonActinsActomyosinAnimalsCaenorhabditis elegansCaenorhabditis elegans ProteinsCell DivisionCytokinesisKymographyMicrotubulesSpindle ApparatusActinsActomyosinCaenorhabditis elegans ProteinsActomyosinC. elegansCortical flowCytokinesisEmbryoMechanosensitivity

Identifiers

PMID31519810
PMCPMC6803361
OpenAlexW2972635014

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.