Evidence map›Paper›PMID 31519590›Full record

ArticleAnticancer research2019

Effects of Colorectal Cancer Risk Factors on the Association Between Aspirin and Colorectal Cancer.

Max E Seaton, Ulrike Peters, Karen C Johnson, Charles Kooperberg, Andrea Bafford, Niha Zubair

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Anticancer research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Max E SeatonDepartment of Surgery, University of Maryland Medical Center, Baltimore, MD, U.S.A. mseaton@som.umaryland.edu.
Ulrike PetersDepartment of Epidemiology, University of Washington, Seattle, WA, U.S.A.
Karen C JohnsonDepartment of Preventative Medicine, University of Tennessee Health Science Center, Memphis, TN, U.S.A.
Charles KooperbergDivision of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, U.S.A.
Andrea BaffordDepartment of Surgery, University of Maryland Medical Center, Baltimore, MD, U.S.A.
Niha ZubairDivision of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, U.S.A.
Fred Hutch Cancer Center · USUniversity of Maryland, Baltimore · USUniversity of Tennessee Health Science Center · USUniversity of Washington · US

Funding

NHLBI NIH HHS HHSN268201100001INHLBI NIH HHS HHSN268201100002INHLBI NIH HHS HHSN268201100004INHLBI NIH HHS HHSN268201100046CNIA NIH HHS HHSN271201100004CWHI NIH HHS HHSN268201100001CWHI NIH HHS HHSN268201100002CWHI NIH HHS HHSN268201100004C
6 · The paper itself

Abstract

BACKGROUND/

aimWe investigated the effect of aspirin on colorectal cancer (CRC) risk among subgroups of women with and without risk factors for CRC. PATIENTS AND

methodsUsing data from the Women's Health Initiative, we estimated hazard ratios for CRC in association with aspirin use, with stratifications by cardiovascular disease (CVD) risk status, family history of CRC, and history of colorectal polypectomy.

resultsAspirin was associated with a lower risk of CRC among women with low/normal or high CVD-risk status; no family history of CRC; or a history of colonoscopy with polypectomy. Aspirin was not associated with CRC among women with a family history of CRC or a history of colonoscopy without polypectomy.

conclusionAspirin was associated with a lower risk of CRC in women at all levels of CVD-risk, in those with a history of colonoscopy with polypectomy, and in those without a family history of CRC.

Indexed as

AgedAged, 80 and overAnti-Inflammatory Agents, Non-SteroidalAspirinColorectal NeoplasmsComorbidityFemaleHumansMaleMiddle AgedRisk AssessmentRisk FactorsAnti-Inflammatory Agents, Non-SteroidalAspirinAspirincardiovascular diseasechemopreventioncolorectal cancerpolypectomyWomen's Health Initiative

Identifiers

PMID31519590
PMCPMC7552814
OpenAlexW2972741173

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.