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ArticleDiabetes research and clinical practice2019

Global and regional diabetes prevalence estimates for 2019 and projections for 2030 and 2045: Results from the International Diabetes Federation Diabetes Atlas, 9

Pouya Saeedi, Inga Petersohn, Paraskevi Salpea, Belma Malanda, Suvi Karuranga, Nigel Unwin, Stephen Colagiuri, Leonor Guariguata, Ayesha A Motala, Katherine Ogurtsova and 4 more

27 registry-linked trialsAbstract readHistorical Article
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In one paragraph

Article in Diabetes research and clinical practice, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 27 registered trials, which are not on this map. Cited by 4,830 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4,830citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05359432 phase4completedstarted 2020, after this paper: background citation

Comparison of Empaglifozin and Vildagliptin in Efficacy and Safety in Type 2 Diabetes Mellitus

Ran2020Enrolled120Registered outcomes10Posted comparisons0ConditionsType 2 DiabetesArmsempagliflozin, vildagliptin
Open the trial in the graph
NCT05367063 phase4completedstarted 2022, after this paper: background citation

Canagliflozin Attenuates CMR-Quantified Myocardial Fibrosis in Patients With Type 2 Diabetes Mellitus at High Cardiovascular Risk

Ran2022Enrolled45Registered outcomes3Posted comparisons0ConditionsCardiovascular Risk, Type 2 DiabetesArmsCanagliflozin 100mg or Sitagliptin 100mg
Open the trial in the graph
NCT06243536 phase4unknown statusstarted 2024, after this paper: background citation

The Effect of Semaglutide on Disordered Eating Behaviour in Type 2 Diabetic Patients

Ran2024Enrolled60Registered outcomes3Posted comparisons0ConditionsDisordered Eating Behaviors, Overweight, Type 2 DiabetesArmssemaglutide, Standard of care
Open the trial in the graph
NCT06767774 phase4recruitingstarted 2025, after this paper: background citation

Comparison of Pitavastatin Plus Ezetimibe Versus High-Intensity Statin Therapy on Risk of New-Onset Diabetes Mellitus in Prediabetic Patients With Atherosclerotic Cardiovascular Disease

Ran2025Enrolled2,000Registered outcomes13Posted comparisons0ConditionsASCVD, Diabetes, StatinArmsCombination therapy, High intensity statin monotherapy
Open the trial in the graph
NCT04542148 phase2active not recruitingnot on this mapstarted 2022, after this paper: background citation

Glycemic Control After Antenatal Corticosteroids in Women With Pregestational and Gestational Diabetes (Close the GAP)

TypeinterventionalSponsorUniversity of Alabama at BirminghamRan2022 to 2026Enrolled120ConditionsDiabetes Mellitus, Type 2, Preterm Birth, Pregnancy, High Risk, Diabetes, GestationalArmsSliding Scale Insulin, Up-Titration of Home Insulin, Continuous Insulin Infusion, Dexcom G6 Professional Continuous Glucose Monitor
NCT04976361 nacompletednot on this map

Macular Vessels Density Before and After Panretinal Photocoagulation in Patients With Proliferative Diabetic Retinopathy

TypeinterventionalSponsorMinia UniversityRan2019 to 2021Enrolled21ConditionsPRPArmsPRP was done using visulas green laser machine (Carl Zeiss Meditec AG Geoschwitzer Str. 51-52,07745 jena, Germany)
NCT04980144 naunknown statusnot on this mapstarted 2023, after this paper: background citation

Impact of Diquafosol Ophthalmic Solution on Tear Film and Dry Eye Symptom in Type 2 Diabetic Dry Eye: A Four-week Randomized Control, Single Masked Pilot Study.

TypeinterventionalSponsorHe Eye HospitalRan2023 to 2023Enrolled101ConditionsDiabetic Eye ProblemsArms3% Diquafosol tetrasodium, 0.1% hyaluronate
NCT05193331 naunknown statusnot on this mapstarted 2023, after this paper: background citation

3% Diquafosol Topical Ophthalmic Solution in Diabetic Patients With Dry Eye

TypeinterventionalSponsorHe Eye HospitalRan2023 to 2023Enrolled70ConditionsDiabetic Eye ProblemsArms3% Diquafosol tetrasodium
NCT05459987 nacompletednot on this mapstarted 2022, after this paper: background citation

Feasibility and Impact of an Intensive Team-based Intervention on Prediabetes Remission in Patients With Coronary Heart Disease

TypeinterventionalSponsorMontreal Heart InstituteRan2022 to 2023Enrolled36ConditionsPrediabetic State, Coronary Heart Disease, Healthy Lifestyle, RemissionArmsLifestyle changes
NCT05551988 completednot on this mapstarted 2021, after this paper: background citation

Predictors of Foot Amputation in Diabetic Foot Ulcers; A Retrospective Study From Pakistan

TypeobservationalSponsorBolan Medical Complex Hospital Quetta PakistanRan2021 to 2022Enrolled110ConditionsDiabetic Foot, Amputation, Antibiotic Resistant Strain, Diabetic Foot UlcerArmsRetrospective observational study of diabetic foot ulcer
NCT05558878 naunknown statusnot on this mapstarted 2022, after this paper: background citation

Effect of Ambroxol on the Inflammatory Markers and Clinical Outcome of Patients With Diabetic Peripheral Neuropathy

TypeinterventionalSponsorAin Shams UniversityRan2022 to 2023Enrolled80ConditionsDiabetic Neuropathy PeripheralArmsAmbroxol Oral Product
NCT05577390 narecruitingnot on this mapstarted 2024, after this paper: background citation

A Physiologic Comparison of Two Approaches to Treating Peripheral Neuropathy

TypeinterventionalSponsorLoma Linda UniversityRan2024 to 2027Enrolled40ConditionsPeripheral Neuropathy With Type 2 DiabetesArmsIntraneural Facilitation Therapy Treatment, Standard Physical Therapy Treatment
NCT05589467 nacompletednot on this mapstarted 2020, after this paper: background citation

What Are the Effects of Potatoes, Utilizing Specific Cooking Methods, on Blood Pressure in Hypertensive Persons With and Without Type II Diabetes Who Follow the DASH Diet for 6 Weeks?

TypeinterventionalSponsorTexas Tech UniversityRan2020 to 2022Enrolled26ConditionsType 2 Diabetes, Blood PressureArmsDASH-FP, DASH-NFP, Control
NCT05597709 recruitingnot on this mapstarted 2022, after this paper: background citation

Prevalence of Metabolic Associated Fatty Liver Disease in Patients With Type 2 Diabetes in Jiangsu Province of China: a Prospective, Multicenter, Real-world Study

TypeobservationalSponsorWuxi Hisky Medical Technology Co LtdRan2022 to 2027Enrolled2,900ConditionsType 2 Diabetes Mellitus in Remission, Metabolic Associated Fatty Liver DiseaseArmsUltrasound attenuation parameter measurement, fasting blood glucose and fasting insulin determination
NCT05609266 completednot on this map

Validation of Non-invasive Risk Models for Prediction of Incident Type 2 Diabetes in a Swedish Population

TypeobservationalSponsorUmeå UniversityRan1990 to 2020Enrolled115,642ConditionsType2diabetes
NCT05682547 nacompletednot on this mapstarted 2022, after this paper: background citation

A Single Center, Randomized, Controlled Trial Comparing the Clinical Efficacy of 3% Diquafosol Tetrasodium and 0.1 % Hyaluronic Acid 0.1% in Diabetic Patients With Dry Eye Disease

TypeinterventionalSponsorHe Eye HospitalRan2022 to 2023Enrolled99ConditionsDiabetic Eye ProblemsArms3% Diquafosol tetrasodium, 0.1% hyaluronate
NCT05874141 nacompletednot on this mapstarted 2023, after this paper: background citation

Comorbidities in Type 2 Diabetes Mellitus: An Observational Study in Kharga City, New Valley Governate, Egypt

TypeinterventionalSponsorNew Valley UniversityRan2023 to 2026Enrolled295ConditionsType 2 DiabetesArmsHBA1C, Lipid profile, including total, LDL, and HDL cholesterol and Triglycerides, Urine analysis and urinary albumin-to-creatinine ratio, Serum creatinine and estimated glomerular filtration rate, Complete blood count
NCT05913726 completednot on this mapstarted 2023, after this paper: background citation

Network of Doctors for Multimorbidity and Diabetes - The NOMAD Intervention: Protocol for Feasibility Trial of Multidisciplinary Team Conferences for People With Diabetes and Multimorbidity

TypeobservationalSponsorOdense University HospitalRan2023 to 2025Enrolled55ConditionsDiabetes Mellitus, Comorbidities and Coexisting Conditions
NCT06054087 naunknown statusnot on this mapstarted 2023, after this paper: background citation

Effectiveness of Electroacupuncture in the Treatment of Diabetic Peripheral Neuropathy: a MulticentreRandomised Controlled Trial

TypeinterventionalSponsorZhejiang Chinese Medical UniversityRan2023 to 2025Enrolled104ConditionsDiabetic Peripheral Neuropathic PainArmsBasal therapy+EA, Basal therapy
NCT06074913 naunknown statusnot on this mapstarted 2023, after this paper: background citation

Early Warning of Diabetic Peripheral Neuropathy by Using Infrared Thermography and the Effectiveness of Electroacupuncture in Its Prevention

TypeinterventionalSponsorZhejiang Chinese Medical UniversityRan2023 to 2025Enrolled200ConditionsDiabetic Peripheral NeuropathyArmsinfrared thermography (IRT), Basal therapy+EA, Basal therapy
NCT06349850 unknown statusnot on this mapstarted 2024, after this paper: background citation

Predictive Value of Serum Uric Acid to High Density Lipoprotein Cholesterol Ratio for Diabetic Kidney Injury in Type 2 Diabetes

TypeobservationalSponsorSohag UniversityRan2024 to 2024Enrolled100ConditionsDiabetic Kidney InjuryArmsserum uric acid level to plasma HDL-c level ratio (UHR)
NCT06513026 narecruitingnot on this mapstarted 2026, after this paper: background citation

Milk for Diabetes Prevention

TypeinterventionalSponsorAlbert Einstein College of MedicineRan2026 to 2028Enrolled40ConditionsLactose Intolerance, Lactose Intolerant, Lactase Persistence, Pre-DiabetesArmsLactose-Containing Milk, Lactose-Free Milk
NCT06518486 nacompletednot on this mapstarted 2024, after this paper: background citation

The Effectiveness of Foot-Ankle Exercise and Walking Exercise on Foot Neuropathy, Stress, Quality of Life, Blood Sugar Markers, Blood Pressure, Ankle-Brachial Index, and BMI Among Diabetes Mellitus Patients

TypeinterventionalSponsorTaipei Medical UniversityRan2024 to 2025Enrolled375ConditionsDiabetic Foot, Diabetes Mellitus, Type 2, Diabetic Neuropathies, Diabetes Type 2ArmsFoot-ankle exercise, Walking exercise, Usual care and health education
NCT06659848 nacompletednot on this mapstarted 2024, after this paper: background citation

the Effect of Fasted Versus Post-meal HIIT on Glycemic Control in Men With Type 2 Diabetes Mellitus

TypeinterventionalSponsorPrince Sattam Bin Abdulaziz UniversityRan2024 to 2024Enrolled123ConditionsType 2 Diabetes Mellitus (T2DM)Armshigh intensity interval training
NCT06783907 nacompletednot on this mapstarted 2023, after this paper: background citation

Technological-based Personalized Care Intervention for Supporting Older People With Diabetes Mellitus

TypeinterventionalSponsorHong Kong Metropolitan UniversityRan2023 to 2025Enrolled60ConditionsDiabetes MellitusArmsNon-invasive blood glucose monitoring, Traditional blood glucose monitoring
NCT07270328 nacompletednot on this mapstarted 2024, after this paper: background citation

A Pilot Study of Feasibility and Exploratory Study for a Definitive Randomised Controlled Trial of Foot-Ankle Versus Walking Exercises in Patients With Diabetes Mellitus: Effects on Neuropathy, Stress, and Quality of Life

TypeinterventionalSponsorTaipei Medical UniversityRan2024 to 2024Enrolled108ConditionsDiabete Mellitus, Diabete Type 2, Diabetic Peripheral Neuropathy, Diabetic FootArmsFoot-ankle exercise group, Walking exercise group, Control group
NCT07669389 nacompletednot on this mapstarted 2025, after this paper: background citation

The Effectiveness of Diabetes Self-Management Intervention on Glycemic Control, Self-management and Psychological Distress for Ethnic Minority Elderly in Rural Areas in Thailand: A Randomized Controlled Trial

TypeinterventionalSponsorTaipei Medical UniversityRan2025 to 2026Enrolled108ConditionsType 2 Diabetes Mellitus (T2DM), Psychological Distress, HyperglycemiaArmsDiabetes Self-Management Education (DSME) Program, Usual Care
3 · Its place in the literature

Who cites it

4,830 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Pooled it
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  6. Trial
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  12. Understanding barriers and facilitators of adherence to lifestyle changes in prediabetes: a qualitative study.International journal of qualitative studies on health and well-being · 2026
    Observational
  13. Observational
  14. Review
  15. Article
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  20. Review

4,770 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Pouya SaeediInternational Diabetes Federation, Brussels, Belgium. Electronic address: pouya.saeedi@idf.org.
Inga PetersohnInternational Diabetes Federation, Brussels, Belgium.
Paraskevi SalpeaInternational Diabetes Federation, Brussels, Belgium.
Belma MalandaInternational Diabetes Federation, Brussels, Belgium.
Suvi KarurangaInternational Diabetes Federation, Brussels, Belgium.
Nigel UnwinMRC Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom.
Stephen ColagiuriThe University of Sydney, School of Medicine, Australia.
Leonor GuariguataThe University of the West Indies, Cave Hill Campus, Barbados.
Ayesha A MotalaDepartment of Diabetes and Endocrinology, Nelson R. Mandela School of Medicine, University of Kwa-Zulu Natal, Durban, South Africa.
Katherine OgurtsovaInstitute for Health Services Research and Health Economics, German Diabetes Center, Leibniz Center for Diabetes Research at the Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany.
Jonathan E ShawClinical and Population Health, Baker Institute, Australia.
Dominic BrightDiabetes Research Unit Cymru, Swansea University, Swansea, United Kingdom.
Rhys WilliamsDiabetes Research Unit Cymru, Swansea University, Swansea, United Kingdom.
IDF Diabetes Atlas Committee

Funding

Medical Research Council MC_UU_12015/5
6 · The paper itself

Abstract

aimsTo provide global estimates of diabetes prevalence for 2019 and projections for 2030 and 2045.

methodsA total of 255 high-quality data sources, published between 1990 and 2018 and representing 138 countries were identified. For countries without high quality in-country data, estimates were extrapolated from similar countries matched by economy, ethnicity, geography and language. Logistic regression was used to generate smoothed age-specific diabetes prevalence estimates (including previously undiagnosed diabetes) in adults aged 20-79 years.

resultsThe global diabetes prevalence in 2019 is estimated to be 9.3% (463 million people), rising to 10.2% (578 million) by 2030 and 10.9% (700 million) by 2045. The prevalence is higher in urban (10.8%) than rural (7.2%) areas, and in high-income (10.4%) than low-income countries (4.0%). One in two (50.1%) people living with diabetes do not know that they have diabetes. The global prevalence of impaired glucose tolerance is estimated to be 7.5% (374 million) in 2019 and projected to reach 8.0% (454 million) by 2030 and 8.6% (548 million) by 2045.

conclusionsJust under half a billion people are living with diabetes worldwide and the number is projected to increase by 25% in 2030 and 51% in 2045.

Indexed as

ForecastingAdultAgedDiabetes MellitusFemaleGlobal HealthHistory, 21st CenturyHumansMaleMiddle AgedPrevalenceYoung AdultDiabetesImpaired glucose toleranceInternational Diabetes FederationPrevalenceProjectionsUndiagnosed

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

and 21 more above

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.