ArticleACS nano2019
Nanodelivery of Mycophenolate Mofetil to the Organ Improves Transplant Vasculopathy.
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Article in ACS nano, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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20citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
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Who cites it
20 citing papers in PubMed, 37 citations in OpenAlex.
- Intraorgan and targeted nanodelivery in organ transplantation of nonhuman primates.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2026Article
- Antioxidant Polymeric and Non-Polymeric Nanoformulations for the Treatment of Autoimmune Diseases.Current issues in molecular biology · 2026Review
- HEV-Targeted Antibody-Drug Conjugate Promotes Long-Term Cardiac Allograft Acceptance.Circulation · 2026Article
- Inhibition of CD154:CD11b interactions using a novel nanotherapeutic improves allograft survival.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2026Article
- Nanomedicine in Organ Transplantation: From Graft Preservation and Repair to Immunomodulation and Monitoring.Theranostics · 2026Review
- Heart Transplantation: Immunological Challenges Revisited.Current cardiology reviews · 2026Review
- Nanotechnology-driven advancements in organ transplantation: Multifaceted strategies for organ preservation, ischemia reperfusion injury, immunomodulation and post-transplant monitoring.Materials today. Bio · 2025Review
- Nanosilicates promote angiogenesis through activation of ROS-mediated WNT/β-catenin pathway.Science advances · 2025Article
- Targeted delivery of IL-21 neutralizing nanotherapeutics to lymph nodes and kidney allografts attenuates B cell alloimmunity.Kidney international · 2025Article
- Recent progress of nanomaterials for diagnosis and treatment of rejection in heart transplantation.Frontiers in bioengineering and biotechnology · 2025Review
- Application of nanomaterials in heart transplantation: a narrative review.Journal of thoracic disease · 2024Review
- Nanoparticle-based T cell immunoimaging and immunomodulatory for diagnosing and treating transplant rejection.Heliyon · 2024Review
- Delivery of costimulatory blockade to lymph nodes promotes transplant acceptance in mice.The Journal of clinical investigation · 2022Article
- A Tissue-Tended Mycophenolate-Modified Nanoparticle Alleviates Systemic Lupus Erythematosus in MRL/International journal of nanomedicine · 2022Article
- The Application of Nanoparticles in Diagnosis and Treatment of Kidney Diseases.International journal of molecular sciences · 2021Review
- Prevention of vascular-allograft rejection by protecting the endothelial glycocalyx with immunosuppressive polymers.Nature biomedical engineering · 2021Article
- ACTH treatment promotes murine cardiac allograft acceptance.JCI insight · 2021Article
- Machine Perfusion of Extended Criteria Donor Organs: Immunological Aspects.Frontiers in immunology · 2020Review
- The Graz Liver Allocation Strategy-Impact of Extended Criteria Grafts on Outcome Considering Immunological Aspects.Frontiers in immunology · 2020Article
- Nanoparticle Platforms for Antigen-Specific Immune Tolerance.Frontiers in immunology · 2020Review
Corrections and comments
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Authors and funding
13 authors at 3 institutions in 1 country.
Mayuko UeharaTransplantation Research Center, Renal Division , Brigham and Women's Hospital, Harvard Medical School , Boston , Massachusetts 02115 , United States.
Baharak BahmaniTransplantation Research Center, Renal Division , Brigham and Women's Hospital, Harvard Medical School , Boston , Massachusetts 02115 , United States.
Liwei JiangTransplantation Research Center, Renal Division , Brigham and Women's Hospital, Harvard Medical School , Boston , Massachusetts 02115 , United States.
Sungwook JungTransplantation Research Center, Renal Division , Brigham and Women's Hospital, Harvard Medical School , Boston , Massachusetts 02115 , United States.
Naima BanouniTransplantation Research Center, Renal Division , Brigham and Women's Hospital, Harvard Medical School , Boston , Massachusetts 02115 , United States.
Vivek KasinathTransplantation Research Center, Renal Division , Brigham and Women's Hospital, Harvard Medical School , Boston , Massachusetts 02115 , United States.
Zhabiz SolhjouTransplantation Research Center, Renal Division , Brigham and Women's Hospital, Harvard Medical School , Boston , Massachusetts 02115 , United States.
Jing ZhaoTransplantation Research Center, Renal Division , Brigham and Women's Hospital, Harvard Medical School , Boston , Massachusetts 02115 , United States.
Farideh OrdikhaniTransplantation Research Center, Renal Division , Brigham and Women's Hospital, Harvard Medical School , Boston , Massachusetts 02115 , United States.
Munhyung BaeDepartment of Biological Chemistry and Molecular Pharmacology , Harvard Medical School , Boston , Massachusetts 02115 , United States.
Nasim AnnabiDepartment of Chemical and Biomolecular Engineering , University of California at Los Angeles , Los Angeles , California 90095-1592 , United States.ORCID 0000-0003-1879-1202
Martina M McGrathTransplantation Research Center, Renal Division , Brigham and Women's Hospital, Harvard Medical School , Boston , Massachusetts 02115 , United States.
Reza AbdiTransplantation Research Center, Renal Division , Brigham and Women's Hospital, Harvard Medical School , Boston , Massachusetts 02115 , United States.ORCID 0000-0003-4789-5422
Brigham and Women's Hospital · USHarvard University · USUniversity of California, Los Angeles · US
Funding
Organ Design and Engineering Training Program (ODET Program)T32EB016652 · NIBIB · BRIGHAM AND WOMEN'S HOSPITAL · PI BONVENTRE, JOSEPH VINCENT · 2014 to 2023
$3.5MA novel approach to delivering therapeutics in heart transplantationR01HL145813 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI ABDI, REZA · 2019 to 2022
$2.6MProtection of organ transplant from ischemia reperfusion injuriesR01AI126596 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI ABDI, REZA · 2016 to 2020
$2.6MLymph Node Delivery in TransplantationU01AI170056 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI ABDI, REZA · 2022 to 2025
$2.3MPI3K-gamma regulates T cell mediated alloimmunityR01HL141815 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI ABDI, REZA · 2018 to 2021
$1.6MNHLBI NIH HHS R01 HL141815NIAID NIH HHS R01 AI126596NIAID NIH HHS U01 AI170056NIBIB NIH HHS T32 EB016652
Abstract
Inflammation occurring within the transplanted organ from the time of harvest is an important stimulus of early alloimmune reactivity and promotes chronic allograft rejection. Chronic immune-mediated injury remains the primary obstacle to the long-term success of organ transplantation. However, organ transplantation represents a rare clinical setting in which the organ is accessible
Indexed as
TransplantsAnimalsDrug Delivery SystemsFemaleGraft RejectionHeart TransplantationHumansHuman Umbilical Vein Endothelial CellsInflammationMaleMiceMice, Inbred C57BLMycophenolic AcidNanomedicineNanoparticlesPreoperative CareMycophenolic Acidchronic rejectionmycophenolate mofetilnanodeliveryselective drug deliverytransplant
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.