Evidence map›Paper›PMID 31518169›Full record

ArticleAmerican journal of physiology. Heart and circulatory physiology2019

Thymine DNA glycosylase is a key regulator of CaMKIIγ expression and vascular smooth muscle phenotype.

YongFeng Liu, Li-Yan Sun, Diane V Singer, Roman Ginnan, Wen Zhao, Frances L Jourd'heuil, David Jourd'heuil, Xiaochun Long, Harold A Singer

Open access · bronzeAbstract read
In one paragraph

Article in American journal of physiology. Heart and circulatory physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

YongFeng LiuDepartment of Molecular and Cellular Physiology, Albany Medical College, Albany, New York.
Li-Yan SunDepartment of Molecular and Cellular Physiology, Albany Medical College, Albany, New York.
Diane V SingerDepartment of Molecular and Cellular Physiology, Albany Medical College, Albany, New York.
Roman GinnanDepartment of Molecular and Cellular Physiology, Albany Medical College, Albany, New York.
Wen ZhaoDepartment of Molecular and Cellular Physiology, Albany Medical College, Albany, New York.
Frances L Jourd'heuilDepartment of Molecular and Cellular Physiology, Albany Medical College, Albany, New York.
David Jourd'heuilDepartment of Molecular and Cellular Physiology, Albany Medical College, Albany, New York.
Xiaochun LongDepartment of Molecular and Cellular Physiology, Albany Medical College, Albany, New York.
Harold A SingerDepartment of Molecular and Cellular Physiology, Albany Medical College, Albany, New York.
Albany Medical Center Hospital · US

Funding

CALCIUM/CALMODULIN ACTIVATED KINIASES IN SMOOTH MUSCLER01HL049426 · NHLBI · WEIS CENTER FOR RESEARCH-GEISINGER CLINC · PI SINGER, HAROLD A · 1994 to 2019
$6.2M
Function and Regulation of TSPAN2 in Vascular DiseaseR01HL139794 · NHLBI · AUGUSTA UNIVERSITY · PI LONG, XIAOCHUN · 2019 to 2023
$2.7M
Role of cytoglobin in promoting smooth muscle cell survival during maladaptive vascular remodelingR01HL142807 · NHLBI · ALBANY MEDICAL COLLEGE · PI JOURD'HEUIL, DAVID · 2019 to 2021
$1.2M
Role of Cytoglobin in Promoting Smooth Muscle Cell Survival During Maladaptive Vascular RemodelingR56HL142807 · NHLBI · ALBANY MEDICAL COLLEGE · PI JOURD'HEUIL, DAVID · 2018 to 2018
$405k
NHLBI NIH HHS R01 HL049426NHLBI NIH HHS R01 HL139794NHLBI NIH HHS R01 HL142807NHLBI NIH HHS R56 HL142807
6 · The paper itself

Abstract

Multifunctional Ca

Indexed as

Cell PlasticityDNA MethylationAnimalsCalcium-Calmodulin-Dependent Protein Kinase Type 2Carotid Artery, CommonCarotid Artery InjuriesCell ProliferationCells, CulturedDisease Models, AnimalGene Expression Regulation, EnzymologicMaleMuscle, Smooth, VascularMyocytes, Smooth MuscleNeointimaPhenotypePromoter Regions, GeneticCalcium-Calmodulin-Dependent Protein Kinase Type 2Camk2g protein, ratThymine DNA GlycosylaseCaMKIIγCaM kinase IIcytosine methylation/demethylationthymine DNA glycosylasevascular injuryvascular smooth muscle

Identifiers

PMID31518169
PMCPMC6879914
OpenAlexW2972467150

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.