ArticleActa bio-medica : Atenei Parmensis2019
On field vaccine effectiveness in three periods of 2018/2019 influenza season in Emilia-Romagna Region.
Article in Acta bio-medica : Atenei Parmensis, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Virological surveillance of SARS-CoV-2 in an Italian Northern area: differences in gender, age and Real Time RT PCR cycle threshold (Ct) values in three epidemic periods.Acta bio-medica : Atenei Parmensis · 2021Article
- Vaccine Effectiveness Against Influenza-Associated Hospitalizations Among Adults, 2018-2019, US Hospitalized Adult Influenza Vaccine Effectiveness Network.The Journal of infectious diseases · 2021Article
- Vaccine hesitancy in COVID-19 times. An update from Italy before flu season starts.Acta bio-medica : Atenei Parmensis · 2020Review
- Virological surveillance of SARS-CoV-2 in an Italian northern area: comparison of Real Time RT PCR cycle threshold (Ct) values in three epidemic periods.Acta bio-medica : Atenei Parmensis · 2020Article
- Vaccine hesitancy : Report of a student study group.Wiener klinische Wochenschrift · 2020Review
- [Influenza vaccination coverage in Lombardy Region: a twenty-year trend analysis (1999-2019)].Acta bio-medica : Atenei Parmensis · 2020Article
- Immunity status against tetanus in young migrants: a seroprevalence study.Acta bio-medica : Atenei Parmensis · 2020Article
- Influenza vaccine effectiveness in children: a retrospective study on eight post-pandemic seasons with trivalent inactivated vaccine.Acta bio-medica : Atenei Parmensis · 2020Article
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Abstract
background and aim of the workEpidemic influenza is associated with significant morbidity and mortality, particularly in people at risk. The vaccine reduces complications, hospitalization and mortality excess, as well as health care and social costs. Aim of the study was to estimate the influenza vaccine effectiveness (VE) in Emilia-Romagna Region during the 2018/2019 season.
methodsWithin the context of virological surveillance conducted at the Regional Reference Laboratory of Parma, nasal/throat swabs were performed by sentinel practitioners and clinicians, on patients with ILI (Influenza-like illness). VE estimates, overall and against subtype A(H1N1)pdm09 and A(H3N2), were evaluated in three periods of the season, using a test-negative case-control design.
resultsFrom November 2018 to April 2019, 2,230 specimens were analyzed: 1,674 (75.1%) performed by clinicians and 556 (24.9%) by sentinel practitioners of the regional network. The season was characterized by the predominant circulation of influenza type A viruses: 57.4% belonged to subtype A(H3N2), 41.2% to subtype A(H1N1)pdm09. 23.5% of patients was vaccinated against influenza with quadrivalent or adjuvate vaccine. The overall VE was -5% (95% CI -33% - 18%) with a decreasing trend during the season. The overall VE against subtype A(H1N1)pdm09 was 39% (95% CI 11% - 58%) and remained stable during the season. The overall VE against subtype A(H3N2) was -43% (95% CI -89% - -9%), and showed an important decreasing trend.
conclusionsThe possibility to make accurate and continuous VE estimates during the season will help to better define the composition of the vaccine for the following season.
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