Evidence map›Paper›PMID 31517525›Full record

ReviewAIDS patient care and STDs2019

Improving the Youth HIV Prevention and Care Cascades: Innovative Designs in the Adolescent Trials Network for HIV/AIDS Interventions.

Sylvie Naar, Michael G Hudgens, Ron Brookmeyer, April Idalski Carcone, Jason Chapman, Shrabanti Chowdhury, Andrea Ciaranello, W Scott Comulada, Samiran Ghosh, Keith J Horvath and 7 more

Open access · greenAbstract readReview
In one paragraph

Review in AIDS patient care and STDs, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 14 institutions in 1 country.

Sylvie NaarCenter for Translational Behavioral Science, Florida State University, Tallahassee, Florida.
Michael G HudgensDepartment of Biostatistics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
Ron BrookmeyerDepartment of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine at UCLA, Los Angeles, California.
April Idalski CarconeDepartment of Family Medicine and Public Health Sciences, Wayne State University School of Medicine, Detroit, Michigan.
Jason ChapmanOregon Social Learning Center, Eugene, Oregon.
Shrabanti ChowdhuryDepartment of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York.
Andrea CiaranelloDivision of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts.
W Scott ComuladaDepartment of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine at UCLA, Los Angeles, California.
Samiran GhoshDepartment of Family Medicine and Public Health Sciences, Wayne State University School of Medicine, Detroit, Michigan.
Keith J HorvathDepartment of Psychology, San Diego State University, San Diego, California.
LaDrea IngramArnold School of Public Health, University of South Carolina, Columbia, South Carolina.
Sara LeGrandDuke Global Health Institute, Duke University, Durham, North Carolina.
Cathy J RebackFriends Research Institute, Los Angeles, California.
Kit SimpsonDepartment of Healthcare Leadership and Management, Medical University of South Carolina, Charleston, South Carolina.
Bonita StantonHackensack Meridian School of Medicine, Seton Hall University, Newark, New Jersey.
Tyrel StarksDepartment of Psychology, City University of New York-Hunter College, New York, New York.
Dallas SwendemanDepartment of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine at UCLA, Los Angeles, California.
Neurobehavioral Systems · USWayne State University · USDuke Institute for Health Innovation · USFlorida State University · USFriends Research Institute · USHackensack Meridian Health · USHunter College · USIcahn School of Medicine at Mount Sinai · USMassachusetts General Hospital · USMedical University of South Carolina · USOregon Social Learning Center · USSan Diego State University · USUniversity of North Carolina at Chapel Hill · USUniversity of South Carolina · US

Funding

Virology, Immunology, and Microbiology CoreP30AI050410 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DAVID M. MARGOLIS · 2001 to 2026
$76.9M
UCLA Rapid, Relevant, Rigorous Implementation Science HubP30MH058107 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI RAPHAEL J LANDOVITZ · 1997 to 2026
$53.5M
Project-003U24HD089880 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI HUDGENS, MICHAEL G, LAVANGE, LISA · 2016 to 2021
$44.3M
The UNC/Emory Center for Innovative Technology (iTech) across the prevention and care continuumU19HD089881 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI HIGHTOW-WEIDMAN, LISA B, SULLIVAN, PATRICK SEAN · 2016 to 2022
$35.8M
Optimizing the HIV Treatment Continuum with a Stepped Care Model for Youth Living with HIVU19HD089886 · NICHD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI FERNANDEZ, MARIA ISABEL, ROTHERAM-BORUS, MARY JANE · 2016 to 2022
$23.4M
Scientific Core (ETR)U19HD089875 · NICHD · WAYNE STATE UNIVERSITY · PI NAAR, SYLVIE · 2016 to 2021
$21.4M
NIAID NIH HHS P30 AI050410NICHD NIH HHS U19 HD089875NICHD NIH HHS U19 HD089881NICHD NIH HHS U19 HD089886NICHD NIH HHS U24 HD089880NIMH NIH HHS P30 MH058107
6 · The paper itself

Abstract

Dramatic decreases in HIV transmission are achievable with currently available biomedical and behavioral interventions, including antiretroviral therapy and pre-exposure prophylaxis. However, such decreases have not yet been realized among adolescents and young adults. The Adolescent Medicine Trials Network (ATN) for HIV/AIDS interventions is dedicated to research addressing the needs of youth at high risk for HIV acquisition as well as youth living with HIV. This article provides an overview of an array of efficient and effective designs across the translational spectrum that are utilized within the ATN. These designs maximize methodological rigor and real-world applicability of findings while minimizing resource use. Implementation science and cost-effectiveness methods are included. Utilizing protocol examples, we demonstrate the feasibility of such designs to balance rigor and relevance to shorten the science-to-practice gap and improve the youth HIV prevention and care continua.

Indexed as

Antiretroviral Therapy, Highly ActivePre-Exposure ProphylaxisAcquired Immunodeficiency SyndromeAdolescentAdolescent BehaviorHIV InfectionsHumansYoung AdultadolescentbehavioralHIVmethods

Identifiers

PMID31517525
PMCPMC6745528
OpenAlexW2972430225

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.