Evidence map›Paper›PMID 31516997›Full record

ArticleJAAD case reports2019

Talimogene laherparepvec induces durable response of regionally advanced Merkel cell carcinoma in 4 consecutive patients.

Brian C Westbrook, T Graham Norwood, Nina L J Terry, Svetlana B McKee, Robert M Conry

Abstract readCase Reports
In one paragraph

Article in JAAD case reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Review
  6. The Evolving Treatment Landscape of Merkel Cell Carcinoma.Current treatment options in oncology · 2023
    Review
  7. Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Review
  13. Article
  14. Article
  15. Talimogene Laherparepvec in Non-Melanoma Cancers.The Journal of clinical and aesthetic dermatology · 2021
    Review
  16. Review
  17. Article
  18. Review
  19. Article
  20. Current concepts and approaches to merkel cell carcinoma.Archives of dermatological research · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Brian C WestbrookUniversity of Alabama at Birmingham School of Medicine, Birmingham, Alabama.
T Graham NorwoodUniversity of Alabama at Birmingham School of Medicine, Birmingham, Alabama.
Nina L J TerryDepartment of Radiology, General Radiology and Cardiopulmonary Section, University of Alabama at Birmingham Medicine, Birmingham, Alabama.
Svetlana B McKeeDivision of Hematology Oncology, University of Alabama at Birmingham, Birmingham, Alabama.
Robert M ConryDivision of Hematology Oncology, University of Alabama at Birmingham, Birmingham, Alabama.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

advanced Merkel cell carcinomaCR, complete responseCT, computed tomographydurable responseFDA, US Food and Drug AdministrationICB, immune checkpoint blockadeimmunotherapyMCC, Merkel cell carcinomaMCPyV, Merkel cell polyomavirusMerkel cell carcinomaoncolytic virusORR, objective response ratePD-L1, programmed death ligand 1PET, positron emission tomographyPFS, progression-free survivalregionally advanced Merkel cell carcinomaSUV, standardized uptake valuestalimogene laherparepvecTVEC, talimogene laherparepvec

Identifiers

PMID31516997
PMCPMC6728723

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.