ArticleArthroplasty today2019
Cobalt cardiomyopathy in hip arthroplasty.
Article in Arthroplasty today, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.
- Cobalt-Induced Cardiomyopathy: Mitochondrial Dysfunction, Oxidative Stress, and Reversible Cardiac Toxicity: A Systematic Review.Cardiovascular toxicology · 2026Pooled it
- Wire-stem fretting and galvanic corrosion as an underrecognized cause of metallosis after hip arthroplasty: A rare case report.Joint diseases and related surgery · 2026Article
- Navigating Transition Metal-Dependent Cell Death: Mechanisms, Crosstalk, and Future Directions.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Review
- Too young for an acquired cardiomyopathy? Cobalt metallosis as a cardiac amyloidosis mimicker.ESC heart failure · 2024Article
- Horror of three synergistic factors in THA: high mechanical stress, dissimilar metals, low elasticity stem: a case report.Arthroplasty (London, England) · 2021Article
- The Mechanism of Metallosis After Total Hip Arthroplasty.Regenerative engineering and translational medicine · 2021Article
- Cobalt-induced cardiomyopathy - do circulating cobalt levels matter?Bone & joint research · 2021Article
- A case report of cobalt cardiomyopathy leading to electric storm and cardiogenic shock: the importance of the orthopaedic background in patients with heart failure of unknown aetiology.European heart journal. Case reports · 2021Article
- Metal-Specific Biomaterial Accumulation in Human Peri-Implant Bone and Bone Marrow.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2020Article
Corrections and comments
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Authors and funding
6 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCobalt toxicity-related cardiomyopathy in hip arthroplasty has recently been reported in the literature. The purpose of this review is to identify and assess available published evidence of cardiomyopathy in hip arthroplasty patients and to derive recommendations for management.
methodsWe evaluated 23 cases reported until October 2018 and stratified them into 3 categories, based upon pre-existing risk factors for cardiomyopathy, histological confirmation, and evidence of systemic signs of cobalt toxicity.
resultsCobalt toxicity was considered to be the definite cause of cardiomyopathy in 8 cases, and probably contributory in 13 cases. Two cases were considered to have developed cardiomyopathy secondary to pre-existing risk factors. Majority of the patients had a good recovery of cardiac function after hip revision and cardiac management, but 5 cases deteriorated and died.
conclusionsAlthough cobalt-related cardiomyopathy has been reported in a small number of cases of hip arthroplasty, a delay or missed diagnosis may lead to significant morbidity and mortality. Timely diagnosis, removal of causative implant, and avoidance of metal articulations in revision for fractured ceramic implants may help in an effective management.
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