Evidence map›Paper›PMID 31516858›Full record

ArticleAvicenna journal of phytomedicine

Gummosin, a sesquiterpene coumarin from

Milad Iranshahy, Faegheh Farhadi, Babak Paknejad, Parvin Zareian, Mehrdad Iranshahi, Masoumeh Karami, Seyed Reza Abtahi

Open access · greenAbstract read
In one paragraph

Article in Avicenna journal of phytomedicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. A Review of Anticancer Activity ofCurrent pharmaceutical design · 2025
    Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Anticancer potential ofWorld journal of biological chemistry · 2023
    Review
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Milad IranshahyDepartment of Pharmacology and Toxicology, Faculty of Medicine, AJA University of Medical Sciences, Tehran, Iran.
Faegheh FarhadiDepartment of Pharmacognosy, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran.
Babak PaknejadDepartment of Pharmacology and Toxicology, Faculty of Medicine, AJA University of Medical Sciences, Tehran, Iran.
Parvin ZareianDepartment of Physiology, School of Medicine, AJA University of Medical Sciences, Tehran, Iran.
Mehrdad IranshahiBiotechnology Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran.
Masoumeh KaramiBiochemistry Department, Faculty of Medicine, AJA University of Medical Sciences, Tehran, Iran.
Seyed Reza AbtahiDepartment of Pharmacology and Toxicology, Faculty of Medicine, AJA University of Medical Sciences, Tehran, Iran.
Aja University of Medical Sciences · IRBiotechnology Research Center · IRMashhad University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe present study was conducted to find cytotoxic compounds from oleo-gum-resin of MATERIALS AND

methodsA dichloromethane extract of asafoetida was subjected to different chromatography analyses (including column chromatography, preparative thin layer chromatography and high performance liquid chromatography) to isolate its bioactive sesquiterpene coumarins. The structures of isolated compounds were elucidated through

resultsIn this study, 10 sesquiterpene coumarins were isolated from oleo-gum-resin of

conclusionThe preferential cytotoxic activity of gummosin against cancer cell lines is reported for the first time in this study.

Indexed as

ApiaceaeCytotoxicityFerula assa-foetidaGummosinMCF-7PC-3

Identifiers

PMID31516858
PMCPMC6727436
OpenAlexW2942899407

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.