Penile cancer with positive nodes: A case of HPV p16-positivity and its significance, implication of data from head and neck cancer.

Cam Nguyen, Stephen Leslie, John Gross, Nicholas Dietz, Subodh M Lele, Gopi Sirineni

Abstract readCase Reports

In one paragraph

Article in Urology case reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Cam NguyenDivision of Radiation Oncology, Creighton University Medical Center, Omaha, NE, USA.

Stephen LeslieDepartment of Urology, Creighton University School of Medicine, Omaha, NE, USA.

John GrossDepartment of Pathology, Creighton University Medical Center, Omaha, NE, USA.

Nicholas DietzDepartment of Pathology, Creighton University Medical Center, Omaha, NE, USA.

Subodh M LeleDepartment of Pathology, University of Nebraska Medical Center, Omaha, NE, USA.

Gopi SirineniDepartment of Radiology, Creighton University Medical Center, Omaha, NE, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Penile cancer is normally discovered in an early stage due to its visibility to the patient. This case report demonstrates a morbidly obese patient with a locally advanced penile cancer hidden by fatty tissue. Biopsy showed P16-positive tumor cells, which responded to concurrent chemo-radiotherapy with no evidence of disease at 24 months of follow-up. We also review the significance of p16-positive cell biology.

Indexed as

Anal cancerChemotherapyHPVp16Penile cancerRadiotherapy

Identifiers

PMID31516836

DOI10.1016/j.eucr.2019.101009

PMCPMC6737329

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.