ReviewCureus2019
The Natural History of Cervical Spondylotic Myelopathy and Ossification of the Posterior Longitudinal Ligament: A Review Article.
Review in Cureus, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 33 citations in OpenAlex.
- Data mining-based detection of the clinical effect on motion style acupuncture therapy combined with conventional acupuncture therapy in chronic neck pain.Technology and health care : official journal of the European Society for Engineering and Medicine · 2022Trial
- Finite element analysis of the effects of different ossification types and spinal canal occupancy rates on dynamic spinal cord stress in cervical ossification of the posterior longitudinal ligament.Frontiers in bioengineering and biotechnology · 2026Article
- Controversies surrounding posterior cervical laminoplasty for cervical spondylotic myelopathy with kyphotic deformity.American journal of translational research · 2026Review
- Knowledge, attitude, and practice of cervical spondylosis in the general public.Scientific reports · 2025Article
- Effects of Preoperative Cervical Range of Motion on Clinical Outcomes Following Posterior Decompression: A Multicenter Study of Patients With Cervical Ossification of the Posterior Longitudinal Ligament.Global spine journal · 2025Article
- Direct anterior decompression in patients with ossification of the posterior longitudinal ligament significantly relieves short-segment spinal cord high signal.BMC musculoskeletal disorders · 2024Article
- Identifying and exploring the favorable factors that help to slow the progression of disease in patients with mild cervical spondylotic myelopathy.Scientific reports · 2024Article
- The "pancake-like" enhancement in cervical spondylotic myelopathy.Radiology case reports · 2024Article
- Resting-state brain plasticity is associated with the severity in cervical spondylotic myelopathy.BMC musculoskeletal disorders · 2024Article
- Cervical Spondylotic Myelopathy-Diagnostics and Clinimetrics.Diagnostics (Basel, Switzerland) · 2024Review
- Laminoplasty versus laminectomy with fusion for treating multilevel degenerative cervical myelopathy.North American Spine Society journal · 2023Article
- Brain connectivity markers in degenerative cervical myelopathy patients with depression for predicting the prognosis following decompression surgery.Frontiers in neurology · 2022Article
- Clinical Efficacy and Safety of Anterior Cervical Decompression versus Segmental Fusion and Posterior Expansive Canal Plasty in the Treatment of Multilevel Cervical Spondylotic Myelopathy.Journal of healthcare engineering · 2022Article
- Investigation of the biomarkers involved in ectopic ossification: The shared mechanism in ossification of the spinal ligament.Frontiers in genetics · 2022Article
- Minimally invasive laminar lift and posterior cervical laminoplasty via the intermuscular approach: a canine model study.Acta cirurgica brasileira · 2022Article
- Factors Significantly Associated with Postoperative Neck Pain Deterioration after Surgery for Cervical Ossification of the Posterior Longitudinal Ligament: Study of a Cohort Using a Prospective Registry.Journal of clinical medicine · 2021Article
- An open-label randomized multi-Centre study to evaluate anterior controllable Antedisplacement and fusion versus posterior Laminoplasty in patients with cervical ossification of the posterior longitudinal ligament: study design and analysis plan (STAR).BMC musculoskeletal disorders · 2021Article
- Japanese Orthopaedic Association Cervical Myelopathy Evaluation Questionnaire as an outcome measure for ossification of posterior longitudinal ligament patients in East Asia: an investigation of reliability, validity, and responsiveness.Annals of translational medicine · 2021Article
- Ossification of the Posterior Longitudinal Ligament in the Cervical, Thoracic, and Lumbar Spine.Cureus · 2021Article
- Cervical Spondylotic Myelopathy with Ossification of Posterior Longitudinal Ligament: Which Is the Most Suitable Surgical Procedure? A Technical Note.Spine surgery and related research · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cervical spondylotic myelopathy (CSM) is the chronic and slow deterioration of cervical spinal cord function. The pathophysiology of this condition is multifactorial, including compression, repetitive trauma, and vascular compromise of the spinal cord. Clinically, it presents as a progressive decline in patients' appendicular neurological function. The natural history of this disease varies but, it is well-known that the duration and degree of compression correlate negatively with prognosis. A mild degree of CSM tends to stabilize with potential improvement over time while more severe CSM tends to progress. Surgical intervention has shown to positively alter the natural history of the disease by halting the progression with some restoration of function. Ossification of the posterior longitudinal ligament (OPLL) is a chronic disease that results in progressive ossification of the posterior longitudinal ligament of the spine. It commonly affects the cervical spine. The etiology is multifactorial in nature, including genetic and environmental factors. The progressive nature of this condition and the resultant cervical spinal stenosis make it one of the main causes of cervical myelopathy (CM). There is no medical therapy for this disease, and surgery is reserved for patients with CM caused by spinal cord compression. In this article, we review the different aspects of the natural history of both CSM and OPLL.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.