Evidence map›Paper›PMID 31516764›Full record

ArticleAmerican journal of cardiovascular disease2019

Testing the obesity paradox in patients on long-term milrinone infusion for end-stage heart failure.

Mina M Benjamin, Sakthi Sundararajan, Samian Sulaiman, Tammy Kindel, David Joyce, Asim A Mohammed

Abstract read
In one paragraph

Article in American journal of cardiovascular disease, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mina M BenjaminDivision of General Internal Medicine, Department of Medicine, Froedtert & The Medical College of Wisconsin 9200 West Wisconsin Avenue Milwaukee, WI 53226-3596, USA.
Sakthi SundararajanDivision of General Internal Medicine, Department of Medicine, Froedtert & The Medical College of Wisconsin 9200 West Wisconsin Avenue Milwaukee, WI 53226-3596, USA.
Samian SulaimanDivision of General Internal Medicine, Department of Medicine, Froedtert & The Medical College of Wisconsin 9200 West Wisconsin Avenue Milwaukee, WI 53226-3596, USA.
Tammy KindelDepartment of Surgery, Froedtert & The Medical College of Wisconsin 9200 West Wisconsin Avenue Milwaukee, WI 53226-3596, USA.
David JoyceDepartment of Surgery, Froedtert & The Medical College of Wisconsin 9200 West Wisconsin Avenue Milwaukee, WI 53226-3596, USA.
Asim A MohammedDivision of Cardiovascular Medicine, Department of Medicine, Froedtert & The Medical College of Wisconsin 9200 West Wisconsin Avenue Milwaukee, WI 53226-3596, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundObese patients with chronic HF have a lower mortality than do non-obese patients with heart failure (HF) i.e. "obesity paradox". We sought to determine the relationship between obesity (defined by body-mass index; BMI) and survival in inotrope-dependent patients with Stage D HF. METHODS AND

resultsWe screened the medical records of adults with ACC/AHA stage D HF who were admitted to our institution between January, 2010 and July, 2018 who were both initiated and discharged on continuous intravenous milrinone. Patients were divided into three groups: non-obese patients (Nob-BMI < 30 kg/m

conclusionIn this retrospective study of stage D inotrope-dependent HF patients, there was trend of an "obesity paradox" with higher survival in the Ob1 group patients compared to NOb and Ob2/3 patients. Ob2/3 patients had the worst survival.

Indexed as

Heart failureinotropesleft ventricular assist devicemilrinoneobesity

Identifiers

PMID31516764
PMCPMC6737350

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.