Evidence map›Paper›PMID 31516763›Full record

ReviewAmerican journal of cardiovascular disease2019

Effect of donor hypertension on renal transplant recipients' blood pressure, allograft outcomes and survival: a systematic review and meta-analysis.

Abdulrahman Altheaby, Sultan Al Dalbhi, Yasser Alghamdi, Turky H Almigbal, Khalid N Alotaibi, Mohammed A Batais, Abdulaziz Alodhayani, Abdullah Alkhushail, Mashhor Alhantoushi, Saad M Alsaad

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In one paragraph

Review in American journal of cardiovascular disease, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Hypertension in kidney transplant recipients.World journal of transplantation · 2022
    Review
  5. New onset hypertension after transplantation.World journal of transplantation · 2022
    Review
  6. Deceased Donor Characteristics and Kidney Transplant Outcomes.Transplant international : official journal of the European Society for Organ Transplantation · 2022
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Abdulrahman AltheabyDepartment of Hepatobiliary Sciences and Organ Transplant Center, King Abdulaziz Medical City Riyadh, Saudi Arabia.
Sultan Al DalbhiDepartment of Adult Nephrology, Prince Sultan Military Medical City Riyadh, Saudi Arabia.
Yasser AlghamdiDepartment of Adult Nephrology, Prince Mohammed Bin Abdulaziz Hospital Riyadh, Saudi Arabia.
Turky H AlmigbalDepartment of Family and Community Medicine, College of Medicine, King Saud University Riyadh, Saudi Arabia.
Khalid N AlotaibiDepartment of Clinical Pharmaceutical Services, Prince Sultan Military Medical City Riyadh, Saudi Arabia.
Mohammed A BataisDepartment of Family and Community Medicine, College of Medicine, King Saud University Riyadh, Saudi Arabia.
Abdulaziz AlodhayaniDepartment of Community and Family Medicine, College of Medicine, King Saud University Riyadh, Saudi Arabia.
Abdullah AlkhushailDepartment of Adult Cardiology, Prince Sultan Cardiac Center Riyadh, Saudi Arabia.
Mashhor AlhantoushiDepartment of Family Medicine, Prince Mohammed Bin Abdulaziz Hospital Riyadh, Saudi Arabia.
Saad M AlsaadDepartment of Family and Community Medicine, College of Medicine, King Saud University Riyadh, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe effect of donor hypertension on the blood pressure of renal transplant recipients and the allograft outcomes are unclear. The aim of this study was to summarize the evidence about the effects of donor hypertension on renal transplant recipients' blood pressure, renal allograft outcomes and mortality.

methodsStudies published from January 1960 to 31 January 2019 in English were identified through a systematic search of six databases; PubMed, Embase, SCOPUS, Web of Science, Cochrane Database of Systematic Reviews, and CINAHL. Eligible observational studies with at least 1 year of follow-up were selected. Pooled estimates were obtained using random effects model.

resultsWe identified 15 papers from eight countries containing data on donor hypertension and renal transplantation carried out between 1963 and 2014. The median (range) follow-up period of the studies was 3.8 (1-11.9) years. The prevalence of post-transplant hypertension among recipients of a renal allograft from a normotensive donor range from 8 to 17.6%, while the prevalence of post-transplant hypertension among recipients of a renal allograft from a hypertensive donor range from 2.9 to 25%. Overall, pooled risk ratios (RR) indicated that donor hypertension was a risk factor for allograft failure or loss among renal transplant recipients (RR 1.31; 95% CI 1.06-1.63: P = 0.014). However, donor hypertension was not a risk factor for mortality among renal transplant recipients (RR 0.996; 95% CI 0.652-1.519: P = 0.984).

conclusionsDonor hypertension increases the risk of post-transplant hypertension among renal transplant recipients and increases the risk of allograft failure, However, donor hypertension was not a risk factor for mortality among renal transplant recipients, Closer monitoring should be given to renal allograft recipients from hypertensive donors, and further well-designed studies are needed to expand our knowledge of the impact of donor hypertension on the survival of renal allograft recipients.

Indexed as

allograft failuredonor hypertensionKidney transplantationmortalityoutcomesrisk factors

Identifiers

PMID31516763
PMCPMC6737352

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.