Evidence map›Paper›PMID 31516749›Full record

ArticleCancer biology & medicine2019

Attenuated

Dong Zhou, Hong Zheng, Quanxing Liu, Xiao Lu, Xufeng Deng, Li Jiang, Bing Hou, Yong Fu, Feng Zhu, Yan Ding and 2 more

Open access · goldAbstract read
In one paragraph

Article in Cancer biology & medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Computational vaccine development against protozoa.Computational and structural biotechnology journal · 2025
    Review
  6. Parasites revive hope for cancer therapy.European journal of medical research · 2024
    Review
  7. Review
  8. Review
  9. A novel enemy of cancer: recent investigations into protozoan anti-tumor properties.Frontiers in cellular and infection microbiology · 2023
    Review
  10. Anti-Tumor Effect of Parasitic Protozoans.Bioengineering (Basel, Switzerland) · 2022
    Review
  11. Frontiers in cell and developmental biology · 2022
    Article
  12. Article
  13. Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Dong ZhouDepartment of Thoracic Surgery, Xinqiao Hospital, Third Military Medical University, Chongqing 400037, China.
Hong ZhengDepartment of Thoracic Surgery, Xinqiao Hospital, Third Military Medical University, Chongqing 400037, China.
Quanxing LiuDepartment of Thoracic Surgery, Xinqiao Hospital, Third Military Medical University, Chongqing 400037, China.
Xiao LuDepartment of Thoracic Surgery, Xinqiao Hospital, Third Military Medical University, Chongqing 400037, China.
Xufeng DengDepartment of Thoracic Surgery, Xinqiao Hospital, Third Military Medical University, Chongqing 400037, China.
Li JiangDepartment of Thoracic Surgery, Xinqiao Hospital, Third Military Medical University, Chongqing 400037, China.
Bing HouDepartment of Thoracic Surgery, Xinqiao Hospital, Third Military Medical University, Chongqing 400037, China.
Yong FuDepartment of Pathogenic Biology, Third Military Medical University, Chongqing 400037, China.
Feng ZhuDepartment of Pathogenic Biology, Third Military Medical University, Chongqing 400037, China.
Yan DingDepartment of Pathogenic Biology, Third Military Medical University, Chongqing 400037, China.
Wenyue XuDepartment of Pathogenic Biology, Third Military Medical University, Chongqing 400037, China.
Jigang DaiDepartment of Thoracic Surgery, Xinqiao Hospital, Third Military Medical University, Chongqing 400037, China.
Army Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveCancer vaccines that rely on tumor antigen-specific CD8

methodsWe constructed GAS/MAGE-A3, a recombinant GAS engineered to express the lung cancer-specific antigen, melanoma-associated antigen 3 (MAGE-A3), and assessed its therapeutic effects against lung cancer.

resultsRobust parasite-specific CD8α

conclusionsThese findings demonstrate that GAS/MAGE-A3 induces a strong MAGE-A3-specific CD8

Indexed as

genetically attenuated sporozoiteslung cancerMAGE-A3malariaVaccine

Identifiers

PMID31516749
PMCPMC6713645
OpenAlexW2947921810

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.