Evidence map›Paper›PMID 31516551›Full record

ArticleBiotechnology for biofuels2019

Modular pathway engineering of key precursor supply pathways for lacto-

Xiaomin Dong, Nan Li, Zhenmin Liu, Xueqin Lv, Jianghua Li, Guocheng Du, Miao Wang, Long Liu

Abstract read
In one paragraph

Article in Biotechnology for biofuels, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Identification of a novel β-1,4-galactosyltransferase fromSynthetic and systems biotechnology · 2026
    Article
  3. Metabolic Engineering ofChem & bio engineering · 2026
    Article
  4. Article
  5. Review
  6. Precursor Quantitation Methods for Next Generation Food Production.Frontiers in bioengineering and biotechnology · 2022
    Review
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xiaomin Dong1Key Laboratory of Food Science and Technology, Ministry of Education, Jiangnan University, Wuxi, 214122 China.
Nan LiState Key Laboratory of Dairy Biotechnology, Shanghai Engineering Research Center of Dairy Biotechnology, Dairy Research Institute, Bright Dairy & Food Co, Ltd, Shanghai, 200436 China.
Zhenmin LiuState Key Laboratory of Dairy Biotechnology, Shanghai Engineering Research Center of Dairy Biotechnology, Dairy Research Institute, Bright Dairy & Food Co, Ltd, Shanghai, 200436 China.
Xueqin Lv3Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, Jiangnan University, Wuxi, 214122 China.
Jianghua Li3Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, Jiangnan University, Wuxi, 214122 China.
Guocheng Du3Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, Jiangnan University, Wuxi, 214122 China.
Miao Wang1Key Laboratory of Food Science and Technology, Ministry of Education, Jiangnan University, Wuxi, 214122 China.
Long Liu3Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, Jiangnan University, Wuxi, 214122 China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLacto-

resultsIn this study, the synthetic pathway of LNnT was constructed by co-expressing the lactose permease (LacY) β-1,3-

conclusionsIn general, this study showed that the LNnT biosynthesis could be significantly increased by optimizing enzymes expression levels and modular pathway engineering for balancing the precursors supply in

Indexed as

Bacillus subtilisHuman milk oligosaccharidesLacto-N-neotetraoseModular pathway engineering

Identifiers

PMID31516551
PMCPMC6732834

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.