ReviewTobacco induced diseases2019
Effect of tobacco on periodontal disease and oral cancer.
Review in Tobacco induced diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 88 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
88 citing papers in PubMed, 4 syntheses or guidelines pooled it, 153 citations in OpenAlex.
- Passive Smoking and Oral Health of Infants, Preschoolers, and Children: A Systematic Review.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2023Pooled it
- Relationship between smoking and postoperative complications of cervical spine surgery: a systematic review and meta-analysis.Scientific reports · 2022Pooled it
- Oral Health Status in Patients with Inflammatory Bowel Diseases: A Systematic Review.International journal of environmental research and public health · 2021Pooled it
- Effect of nicotine exposure on the rate of orthodontic tooth movement: A meta-analysis based on animal studies.PloS one · 2021Pooled it
- Efficacy of antioxidants supplementation as an adjunct to non-surgical periodontal therapy: an umbrella meta-analysis.Odontology · 2026Review
- Association of tobacco use with periodontal status and salivary biomarkers (thiocyanate and pH) among construction workers: a cross-sectional study.The Saudi dental journal · 2026Article
- The Impact of Limited Access to Dental Care on Emergency Room Service Utilization: A Study of Primary Healthcare in a Rural Inland Region of Portugal.Dentistry journal · 2026Article
- Gingival Blood Vessels in Smokers and Nonsmokers: A Scoping Review.European journal of dentistry · 2026Article
- Comparison of gingival phenotype among adult male naswar users, cigarette smokers and non-tobacco users: a cross-sectional study.Scientific reports · 2026Article
- Smoking Cigarettes and Tooth Loss in Adults: A Population-Based Analysis.Journal of clinical medicine · 2026Article
- Tobacco-derived particulates and the periodontal axis: Distinct cytotoxic and stress-related mechanisms in human gingival fibroblasts.Scientific reports · 2026Article
- The role of smoking habits in periodontal health and disease: A cross-sectional study.Tobacco induced diseases · 2026Article
- A comparative study of implant survival rates in smokers and non-smokers.Bioinformation · 2026Article
- Adjunctive Use of Ozone Therapy in Treating Periodontitis in Smokers: A Prospective Split-Mouth Study.International journal of dentistry · 2026Article
- Oral health and healthy aging: A multiregional review.JAR life · 2026Review
- Alveolar Bone Loss at Maxillary and Mandibular Permanent First Molars in Periodontitis Patients: A Descriptive Cross-sectional Study.JNMA; journal of the Nepal Medical Association · 2025Article
- Behavioural Change Interventions for Preventing Periodontal Disease in Older Adults: A Literature Review.Geriatrics (Basel, Switzerland) · 2025Review
- Association Between Tobacco and Periodontal Disease in Latin America from 2000 to 2024: Cross-Sectional Analysis of Global Burden of Disease Study.Journal of clinical medicine · 2025Article
- Approaches for cessation and elimination of tobacco to atttain sustainable development goal.Journal of family medicine and primary care · 2025Review
- Periodontal Disease in Saudi Arabia: A Systematic Review of Prevalence and Associated Risk Factors.Diagnostics (Basel, Switzerland) · 2025Review
28 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionPeriodontal disease and oral cancer are common health hazards. Epidemiological investigations show that smoking, periodontal disease and oral cancer are closely related. Tobacco is one of the major risk factors for periodontitis and oral cancer.
methodsA systematic literature review was performed. To identify relevant studies, the following online databases were searched using specific keywords: PubMed, Web of Science and CNKI.
resultsTobacco not only possesses an addictive effect, but it aggravates periodontal disease by promoting the invasion of pathogenic bacteria, inhibiting autoimmune defense, aggravating the inflammatory reaction, and aggravating the loss of alveolar bone. According to current evidence, tobacco significantly aggravates the development and progression of periodontal disease and oral cancer, and periodontal disease may be related to the prevalence of oral cancer.
conclusionsClinicians should strongly recommend that smokers undertake a strategy to stop smoking to avoid the exacerbation of nicotine-related periodontal disease and to reduce the incidence of oral cancer.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.