Evidence map›Paper›PMID 31516275›Full record

ArticleAnnals of pediatric cardiology

Different habitus but similar electrocardiogram: Cardiac repolarization parameters in children - Comparison of elite athletes to obese children.

Christian Paech, Janina Moser, Ingo Dähnert, Franziska Wagner, Roman Antonin Gebauer, Toralf Kirsten, Mandy Vogel, Wieland Kiess, Antje Körner, Bernd Wolfarth and 1 more

Open access · diamondAbstract read
In one paragraph

Article in Annals of pediatric cardiology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Christian PaechDepartment for Pediatric Cardiology, University of Leipzig - Heart Center, Leipzig, Germany.
Janina MoserDepartment for Pediatric Cardiology, University of Leipzig - Heart Center, Leipzig, Germany.
Ingo DähnertDepartment for Pediatric Cardiology, University of Leipzig - Heart Center, Leipzig, Germany.
Franziska WagnerDepartment for Pediatric Cardiology, University of Leipzig - Heart Center, Leipzig, Germany.
Roman Antonin GebauerDepartment for Pediatric Cardiology, University of Leipzig - Heart Center, Leipzig, Germany.
Toralf KirstenLIFE Child (Leipzig Research Center for Civilization Diseases), University of Leipzig, Leipzig, Germany.
Mandy VogelLIFE Child (Leipzig Research Center for Civilization Diseases), University of Leipzig, Leipzig, Germany.
Wieland KiessLIFE Child (Leipzig Research Center for Civilization Diseases), University of Leipzig, Leipzig, Germany.
Antje KörnerLIFE Child (Leipzig Research Center for Civilization Diseases), University of Leipzig, Leipzig, Germany.
Bernd WolfarthUniversity of Leipzig, Institute for Applied Scientific Training, Leipzig, Germany.
Jan WüstenfeldUniversity of Leipzig, Institute for Applied Scientific Training, Leipzig, Germany.
Leipzig University · DELeipzig Heart Institute · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe standard 12-lead electrocardiogram (ECG) remains a widely used tool in the basic cardiac evaluation of children and adolescents. With the emergence of inherited arrhythmia syndromes, the period of cardiac repolarization has been the focus of attention. So far, data on cardiac repolarization and its normal variants in healthy children are scarce. This may cause uncertainties in the differentiation between pathologies and normal variants. As abnormal autonomic regulation seems to be a major influencing factor on cardiac repolarization, this study aimed to evaluate the parameters of cardiac repolarization of children in extremely good physical shape to obese children to improve knowledge about cardiac repolarization in these subgroups of pediatric patients that are vastly affected by the alterations of autonomic regulation.

methodsA total of 426 pediatric volunteers (84 lean, healthy controls; 130 obese healthy pediatric volunteers; and 212 elite athletes) were enrolled in the study, and the parameters of cardiac repolarization were determined in 12-lead ECG.

resultsMost importantly, there were no pathological findings, neither in the healthy controls nor in the obese or athletes. Athletes showed overall shorter corrected QT intervals than children from the other groups. This is also true if a correction of the QT interval is performed using the Hodges formula to avoid bias due to a tendency to lower heart rates in athletes. Athletes showed the shortest Tpeak-to-end ratios between the groups. The comparison of athletes from primarily strength and power sports versus those from endurance sports showed endurance-trained athletes to have significantly longer QT intervals.

conclusionsThis study suggests that neither obesity nor extensive sports seems to result in pathological cardiac repolarization parameters in healthy children. Therefore, pathology has to be assumed if abnormal repolarization parameters are seen and might not be simply attributed to the child's habitus or an excellent level of fitness.

Indexed as

Athletecardiac repolarizationchildrenlong QTobesity

Identifiers

PMID31516275
PMCPMC6716330
OpenAlexW2956467787

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.