Evidence map›Paper›PMID 31516223›Full record

ArticleJournal of oral and maxillofacial pathology : JOMFP

Characterization of oral fibroblasts: An

Pooja Adtani, Malathi Narasimhan, Kannan Ranganathan, Alan Punnoose, Prathibha Prasad, Prabhu Manickam Natarajan

Abstract read
In one paragraph

Article in Journal of oral and maxillofacial pathology : JOMFP. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Effects of low-level laser irradiation on canine fibroblasts.The Journal of veterinary medical science · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Pooja AdtaniDepartment of Oral Pathology, College of Dentistry, Gulf Medical University, Ajman, United Arab Emirates.
Malathi NarasimhanDepartment of Oral Pathology and Microbiology, Faculty of Dental Sciences, Sri Ramachandra Institute of Higher Education and Research, Chennai, Tamil Nadu, India.
Kannan RanganathanDepartment of Oral and Maxillofacial Pathology, Ragas Dental College, Chennai, Tamil Nadu, India.
Alan PunnooseResearch Center for Regenerative Medicine and Stem Cell Research, Central Research Facility, Sri Ramachandra Institute of Higher Education and Research, Chennai, Tamil Nadu, India.
Prathibha PrasadDepartment of Oral Pathology, College of Dentistry, Gulf Medical University, Ajman, United Arab Emirates.
Prabhu Manickam NatarajanDepartment of Periodontics, College of Dentistry, Gulf Medical University, Ajman, United Arab Emirates.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOral submucous fibrosis (OSMF) is a chronic debilitating condition of the oral mucosa that has been classified as a potentially malignant disorder with a malignant transformation rate of 2%-8%. Several

aimTo establish an SETTING AND

designMATERIALS AND METHODOLOGY: Primary cell culture protocol was performed after obtaining normal oral tissue. Karyotyping was performed to rule out chromosomal abnormalities. Immunofluorescence staining was carried with a panel of fibroblast-specific markers (vimentin, phalloidin, transforming growth factor-β receptor 1 [TGFβR1] and s100a4) and Masson trichrome staining (MTS) to demonstrate the presence of extracellular matrix (ECM) qualitatively.

resultsA monolayer of oral fibroblasts was observed on the 9

conclusionThe present study lays down a protocol to design and characterize primary buccal fibroblast cell culture model that would aid researchers in performing

Indexed as

Fibrosisoral fibroblastsphalloidintransforming growth factor

Identifiers

PMID31516223
PMCPMC6714264

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.