ArticleJournal of cardiovascular electrophysiology2019
Physical, cognitive, and psychosocial conditions in relation to anticoagulation satisfaction among elderly adults with atrial fibrillation: The SAGE-AF study.
Article in Journal of cardiovascular electrophysiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
18 citing papers in PubMed, 22 citations in OpenAlex.
- The prevalence and burden of chronic kidney disease, patterns of anticoagulation prescribing, and major bleeding risk in older adults with atrial fibrillation.BMC geriatrics · 2025Article
- Need for Engagement in Stroke Prevention Shared Decision-Making in Older Adults with Atrial Fibrillation and Multimorbidity.Advances in geriatric medicine and research · 2025Article
- Factors influencing self-control in older patients with atrial fibrillation following radiofrequency catheter ablation: a cross-sectional study based on triadic reciprocal determinism.BMC geriatrics · 2025Article
- Role of Cognitive Frailty in Older Adults With Cardiovascular Disease.Journal of the American Heart Association · 2024Review
- Global epidemiology of mental disorder in atrial fibrillation between 1998-2021: A systematic review and meta-analysis.World journal of psychiatry · 2024Article
- Polygenic Risk Score-Based Association Analysis of Speech-in-Noise and Hearing Threshold Measures in Healthy Young Adults with Self-reported Normal Hearing.Journal of the Association for Research in Otolaryngology : JARO · 2023Article
- Differential effect of anticoagulation according to cognitive function and frailty in older patients with atrial fibrillation.Journal of the American Geriatrics Society · 2023Article
- Presence of Geriatric Conditions Is Prognostic of Major Bleeding in Older Patients with Atrial Fibrillation: a Cohort Study.Journal of general internal medicine · 2022Article
- The Influence of Frailty Syndrome and Dementia on the Convenience and Satisfaction with Oral Anticoagulation Treatment in Elderly Patients with Atrial Fibrillation.International journal of environmental research and public health · 2022Article
- Association between risk of obstructive sleep apnea and cognitive performance, frailty, and quality of life among older adults with atrial fibrillation.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2022Article
- Satisfaction With Oral Anticoagulants Among Patients With Atrial Fibrillation: A Prospective Observational Study.CJC open · 2021Article
- Social determinants of atrial fibrillation.Nature reviews. Cardiology · 2021Review
- Factors Associated With Patient Engagement in Shared Decision-Making for Stroke Prevention Among Older Adults with Atrial Fibrillation.Canadian geriatrics journal : CGJ · 2021Article
- Prognostic value of geriatric conditions for death and bleeding in older patients with atrial fibrillation.International journal of cardiology. Heart & vasculature · 2021Article
- Stroke prevention strategies in high-risk patients with atrial fibrillation.Nature reviews. Cardiology · 2021Review
- Self-reported risk of stroke and factors associated with underestimation of stroke risk among older adults with atrial fibrillation: the SAGE-AF study.Journal of geriatric cardiology : JGC · 2020Article
- Hearing loss and cognitive decline among older adults with atrial fibrillation: the SAGE-AF study.Journal of geriatric cardiology : JGC · 2020Article
- Factors Associated with Moderate Physical Activity Among Older Adults with Atrial Fibrillation.Journal of atrial fibrillationArticle
Corrections and comments
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Authors and funding
10 authors at 5 institutions in 1 country.
Funding
Abstract
backgroundSuccessful anticoagulation is critical for stroke prevention in adults with atrial fibrillation (AF). Anticoagulation satisfaction is a key indicator of treatment success. While physical, cognitive, and psychosocial limitations are common in elderly AF patients, their associations with anticoagulation satisfaction are unknown.
objectiveExamine whether anticoagulation satisfaction differs among AF patients with and without physical, cognitive, and psychosocial conditions.
methodsThe study comprised AF patients greater than or equal to 65 years old who were prescribed an oral anticoagulant (warfarin 57%; direct oral anticoagulant [DOAC] 43%). Frailty, cognitive function, social support, depressive symptoms, vision, hearing, and anxiety were assessed using validated measures. Anticoagulation satisfaction was measured using the anticlot treatment scale.
resultsParticipants (n = 1037, 50% female) were on average 76 years old. The following conditions were prevalent: frailty (14%), cognitive impairment (42%), social isolation (13%), vision impairment (35%), hearing impairment (36%), depression (29%), and anxiety (24%). Average anticlot treatment burden scale was 55 out of 60 (lower burden scales indicating higher perceived burden). Patients with high perceived burden were older, more likely to be female, and receive warfarin. After adjusting for confounders, visual impairment (adjusted odds ratio [95% confidence interval]: 1.7 [1.2-2.4]), depressive symptoms (2.4 [1.6-3.7]), and anxiety (1.8 [1.2-2.7]) were significantly associated with high perceived burden. Different conditions were associated with high perceived burden in warfarin vs DOAC users.
conclusionPhysical, cognitive, and psychosocial limitations are prevalent and associated with high perceived anticoagulation burden among elderly AF adults. These conditions merit consideration in anticoagulation prescribing.
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Registered trials
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