Evidence map›Paper›PMID 31515825›Full record

ArticleChemistry (Weinheim an der Bergstrasse, Germany)2019

Distorted Phthalocyanines by Click Chemistry: Photoacoustic, Photothermal, and Surface-Enhanced Resonance Raman Studies.

Waqar Rizvi, Naxhije Berisha, Christopher Farley, N V S Dinesh K Bhupathiraju, Chrysafis Andreou, Emaad Khwaja, German V Fuentes, Moritz F Kircher, Ruomei Gao, Charles Michael Drain

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemistry (Weinheim an der Bergstrasse, Germany), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Waqar RizviDepartment of Chemistry, Hunter College of the City University of New York, New York, New York, 10065, USA.ORCID http://orcid.org/0000-0002-2415-2485
Naxhije BerishaDepartment of Chemistry, Hunter College of the City University of New York, New York, New York, 10065, USA.ORCID http://orcid.org/0000-0003-1067-1150
Christopher FarleyDepartment of Chemistry, Hunter College of the City University of New York, New York, New York, 10065, USA.ORCID http://orcid.org/0000-0002-7787-5134
N V S Dinesh K BhupathirajuDepartment of Chemistry, Hunter College of the City University of New York, New York, New York, 10065, USA.ORCID http://orcid.org/0000-0002-5885-3722
Chrysafis AndreouDepartment of Radiology, Memorial Sloan Kettering Cancer Center New York, New York, 10065, USA.ORCID http://orcid.org/0000-0002-3464-9110
Emaad KhwajaDepartment of Chemistry, Hunter College of the City University of New York, New York, New York, 10065, USA.ORCID http://orcid.org/0000-0002-0205-8455
German V FuentesInstitute for Cancer Research and Education, SUNY Old Westbury, Old Westbury, New York, 11568, USA.
Moritz F KircherDepartment of Radiology, Memorial Sloan Kettering Cancer Center New York, New York, 10065, USA.ORCID http://orcid.org/0000-0003-1575-1467
Ruomei GaoInstitute for Cancer Research and Education, SUNY Old Westbury, Old Westbury, New York, 11568, USA.ORCID http://orcid.org/0000-0001-6240-9934
Charles Michael DrainDepartment of Chemistry, Hunter College of the City University of New York, New York, New York, 10065, USA.ORCID http://orcid.org/0000-0003-2541-2813

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
Ultrabright Theranostic SERRS Nanoparticles for Gastrointestinal EndoscopyR01CA222836 · NCI · STANFORD UNIVERSITY · PI ROGALLA, STEPHAN · 2018 to 2023
$3.4M
MRI-Photoacoustic-Raman Nanostars for Pre- and Intraoperative Multimodal ImagingR01EB017748 · NIBIB · SLOAN-KETTERING INST CAN RESEARCH · PI KIRCHER, MORITZ FLORIAN · 2014 to 2017
$1.6M
National Science Foundation CHE-1610755NCI NIH HHS P30 CA008748NCI NIH HHS R01 CA222836NIBIB NIH HHS R01 EB017748
6 · The paper itself

Abstract

Distortion of nominally planar phthalocyanine macrocycles affects the excited state dynamics in that most of the excited-state energy decays through internal conversion. A click-type annulation reaction on a perfluorophthalocyanine platform appending a seven-membered ring to the β-positions on one or more of the isoindoles distorts the macrocycle and modulates solubility. The distorted derivative enables photoacoustic imaging, photothermal effects, and strong surface-enhanced resonance Raman signals.

Indexed as

click chemistryphotoacoustic imagingphotothermal therapyphthalocyaninesRaman spectroscopy

Identifiers

PMID31515825
PMCPMC6861660

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.