Evidence map›Paper›PMID 31515690›Full record

ArticleUpdates in surgery2020

Is follow-up still mandatory more than 5 years after surgery for colorectal cancer?

Alice Frontali, Benjamin Benichou, Ionut Valcea, Léon Maggiori, Justine Prost À la Denise, Yves Panis

Abstract read
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In one paragraph

Article in Updates in surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Alice FrontaliService de Chirurgie Colorectale, Pôle des Maladies de l'Appareil Digestif (PMAD), Hôpital Beaujon-Assistance Publique des Hôpitaux de Paris (APHP), Université Paris VII (Denis Diderot), 100 boulevard du Général Leclerc, Clichy, 92110, France.
Benjamin BenichouService de Chirurgie Colorectale, Pôle des Maladies de l'Appareil Digestif (PMAD), Hôpital Beaujon-Assistance Publique des Hôpitaux de Paris (APHP), Université Paris VII (Denis Diderot), 100 boulevard du Général Leclerc, Clichy, 92110, France.
Ionut ValceaService de Chirurgie Colorectale, Pôle des Maladies de l'Appareil Digestif (PMAD), Hôpital Beaujon-Assistance Publique des Hôpitaux de Paris (APHP), Université Paris VII (Denis Diderot), 100 boulevard du Général Leclerc, Clichy, 92110, France.
Léon MaggioriService de Chirurgie Colorectale, Pôle des Maladies de l'Appareil Digestif (PMAD), Hôpital Beaujon-Assistance Publique des Hôpitaux de Paris (APHP), Université Paris VII (Denis Diderot), 100 boulevard du Général Leclerc, Clichy, 92110, France.
Justine Prost À la DeniseService de Chirurgie Colorectale, Pôle des Maladies de l'Appareil Digestif (PMAD), Hôpital Beaujon-Assistance Publique des Hôpitaux de Paris (APHP), Université Paris VII (Denis Diderot), 100 boulevard du Général Leclerc, Clichy, 92110, France.
Yves PanisService de Chirurgie Colorectale, Pôle des Maladies de l'Appareil Digestif (PMAD), Hôpital Beaujon-Assistance Publique des Hôpitaux de Paris (APHP), Université Paris VII (Denis Diderot), 100 boulevard du Général Leclerc, Clichy, 92110, France. yves.panis@aphp.fr.ORCID http://orcid.org/0000-0001-9553-9727

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe aim of this study was to assess if to prolong follow-up (FU) more than 5 years after surgery for colorectal cancer (CRC) is justified or not.

methodsPatients who underwent surgery for a CRC before 2013 and without any tumor recurrence (or synchronous metastases) during the first 5 years after surgery were identified from our database and included.

resultsBetween 1996 and 2012, 121 patients operated for rectal (RC) (median of FU of 84 months; range 60-211) and 97 with colonic cancer (CC) (median of FU of 78 months; range 60-139), without any tumor recurrence (or synchronous metastases) during the first 5 years after surgery, presented a late tumor recurrence: 13/121 RC (10.7%) versus 2/97 CC (2.1%) (p = 0.014); 8/13 recurrences in RC (61.5%) were observed after neoadjuvant radiochemotherapy, and 9/13 (69.2%) in pN0 tumors. Among the 13 recurrences, 3 had both local and metastatic recurrences (23%), 5 an isolated local recurrence (38.5%) and 5 an isolated metastatic recurrence (38.5%). After surgery for CC, the 2 recurrences were observed in patients with T3N0 tumors.

conclusionAfter surgery for a CRC, in patients without tumor recurrence during the first 5 years after surgery, follow-up after 5 years must be continued in rectal cancer patients because of a 10.7% rate of late recurrence. On the opposite, after surgery for colon cancer the 2% rate of late recurrence after 5 years suggested that only patients with pT3-T4 colonic cancer could probably be followed more than 5 years after surgery.

Indexed as

Follow-Up StudiesChemoradiotherapy, AdjuvantColorectal NeoplasmsHumansTime FactorsColorectal cancerFollow-up programSurgeryTumor recurrence

Identifiers

PMID31515690

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.