Evidence map›Paper›PMID 31515389›Full record

ArticleScience (New York, N.Y.)2019

Mitoribosomal small subunit biogenesis in trypanosomes involves an extensive assembly machinery.

Martin Saurer, David J F Ramrath, Moritz Niemann, Salvatore Calderaro, Céline Prange, Simone Mattei, Alain Scaiola, Alexander Leitner, Philipp Bieri, Elke K Horn and 4 more

Abstract read
PubMed Publisher
In one paragraph

Article in Science (New York, N.Y.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
8.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 78 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. The late stages of yeast mitoribosome large subunit biogenesis.Biochimica et biophysica acta. Molecular cell research · 2025
    Article
  5. Article
  6. Mitochondrial Ribosomal Proteins and Cancer.Medicina (Kaunas, Lithuania) · 2025
    Review
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Mitoribosome Biogenesis.Methods in molecular biology (Clifton, N.J.) · 2023
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Martin Saurer *Department of Biology, Institute of Molecular Biology and Biophysics, ETH Zurich, Otto-Stern-Weg 5, CH-8093 Zurich, Switzerland.ORCID 0000-0001-8181-6711
David J F Ramrath *Department of Biology, Institute of Molecular Biology and Biophysics, ETH Zurich, Otto-Stern-Weg 5, CH-8093 Zurich, Switzerland.ORCID 0000-0002-8985-5165
Moritz Niemann *Department of Chemistry and Biochemistry, University of Bern, Freiestrasse 3, CH-3012 Bern, Switzerland.ORCID 0000-0002-3351-9234
Salvatore CalderaroDepartment of Chemistry and Biochemistry, University of Bern, Freiestrasse 3, CH-3012 Bern, Switzerland.
Céline PrangeDepartment of Biology, Institute of Molecular Biology and Biophysics, ETH Zurich, Otto-Stern-Weg 5, CH-8093 Zurich, Switzerland.
Simone MatteiDepartment of Biology, Institute of Molecular Biology and Biophysics, ETH Zurich, Otto-Stern-Weg 5, CH-8093 Zurich, Switzerland.ORCID 0000-0002-2005-8977
Alain ScaiolaDepartment of Biology, Institute of Molecular Biology and Biophysics, ETH Zurich, Otto-Stern-Weg 5, CH-8093 Zurich, Switzerland.ORCID 0000-0003-3233-3910
Alexander LeitnerDepartment of Biology, Institute of Molecular Systems Biology, Otto-Stern-Weg 3, ETH Zurich, CH-8093 Zurich, Switzerland.ORCID 0000-0003-4126-0725
Philipp BieriDepartment of Biology, Institute of Molecular Biology and Biophysics, ETH Zurich, Otto-Stern-Weg 5, CH-8093 Zurich, Switzerland.ORCID 0000-0001-9031-2945
Elke K HornDepartment of Chemistry and Biochemistry, University of Bern, Freiestrasse 3, CH-3012 Bern, Switzerland.
Marc LeibundgutDepartment of Biology, Institute of Molecular Biology and Biophysics, ETH Zurich, Otto-Stern-Weg 5, CH-8093 Zurich, Switzerland.ORCID 0000-0002-0902-5859
Daniel BoehringerDepartment of Biology, Institute of Molecular Biology and Biophysics, ETH Zurich, Otto-Stern-Weg 5, CH-8093 Zurich, Switzerland.ORCID 0000-0002-6666-8447
André SchneiderDepartment of Chemistry and Biochemistry, University of Bern, Freiestrasse 3, CH-3012 Bern, Switzerland. andre.schneider@dcb.unibe.ch ban@mol.biol.ethz.ch.ORCID 0000-0001-5421-0909
Nenad BanDepartment of Biology, Institute of Molecular Biology and Biophysics, ETH Zurich, Otto-Stern-Weg 5, CH-8093 Zurich, Switzerland. andre.schneider@dcb.unibe.ch ban@mol.biol.ethz.ch.ORCID 0000-0002-9527-210X
ETH Zurich · CHUniversity of Bern · CH

Funding

Swiss National Science Foundation
6 · The paper itself

Abstract

Mitochondrial ribosomes (mitoribosomes) are large ribonucleoprotein complexes that synthesize proteins encoded by the mitochondrial genome. An extensive cellular machinery responsible for ribosome assembly has been described only for eukaryotic cytosolic ribosomes. Here we report that the assembly of the small mitoribosomal subunit in

Indexed as

Cryoelectron MicroscopyMitochondrial ProteinsMitochondrial RibosomesModels, MolecularNucleic Acid ConformationProtein Structure, QuaternaryRibosomal ProteinsRNA InterferenceRNA, RibosomalRNA StabilityTrypanosoma brucei bruceiMitochondrial ProteinsRibosomal ProteinsRNA, Ribosomal

Identifiers

PMID31515389
OpenAlexW2973172561

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.