Evidence map›Paper›PMID 31515286›Full record

ArticleGenome research2019

A novel assay to screen siRNA libraries identifies protein kinases required for chromosome transmission.

Mikhail Liskovykh, Nikolay V Goncharov, Nikolai Petrov, Vasilisa Aksenova, Gianluca Pegoraro, Laurent L Ozbun, William C Reinhold, Sudhir Varma, Mary Dasso, Vadim Kumeiko and 4 more

Open access · bronzeAbstract read
In one paragraph

Article in Genome research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. The role of TAOK3 in cancer progression and development as a prognostic marker: A pan-cancer analysis study.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2024
    Article
  6. The reckoning of chromosomal instability: past, present, future.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2024
    Review
  7. Article
  8. Article
  9. Ectopic expression of meiotic cohesin generates chromosome instability in cancer cell line.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  10. Article
  11. Inherited and de novo variants extend the etiology ofCold Spring Harbor molecular case studies · 2022
    Article
  12. Novel assay to measure chromosome instability identifiesFrontiers in bioengineering and biotechnology · 2022
    Article
  13. Article
  14. The Diverse Roles of TAO Kinases in Health and Diseases.International journal of molecular sciences · 2020
    Review
  15. Human AlphoidCells · 2020
    Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 6 countries.

Mikhail Liskovykh *Developmental Therapeutics Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.
Nikolay V Goncharov *Developmental Therapeutics Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.
Nikolai PetrovDevelopmental Therapeutics Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.
Vasilisa AksenovaDivision of Molecular and Cellular Biology, National Institute for Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892, USA.
Gianluca PegoraroHigh-Throughput Imaging Facility, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.
Laurent L OzbunHigh-Throughput Imaging Facility, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.
William C ReinholdDevelopmental Therapeutics Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.
Sudhir VarmaDevelopmental Therapeutics Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.
Mary DassoDivision of Molecular and Cellular Biology, National Institute for Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892, USA.
Vadim KumeikoSchool of Biomedicine, Far Eastern Federal University, A.V. Zhirmunsky National Scientific Center of Marine Biology, Far Eastern Branch of Russian Academy of Sciences, Vladivostok, 690000, Russia.
Hiroshi MasumotoLaboratory of Chromosome Engineering, Department of Frontier Research and Development, Kazusa DNA Research Institute, Kisarazu, Chiba 292-0818d, Japan.
William C EarnshawWellcome Centre for Cell Biology, University of Edinburgh, Edinburgh EH9 3JR, United Kingdom.
Vladimir LarionovDevelopmental Therapeutics Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.
Natalay KouprinaDevelopmental Therapeutics Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.
National Institutes of Health · USFar Eastern Federal University · RUKazusa DNA Research Institute · JPWellcome Centre for Cell Biology · GB

Funding

Wellcome Trust 073915
6 · The paper itself

Abstract

One of the hallmarks of cancer is

Indexed as

AneuploidyCalcium-Calmodulin-Dependent Protein Kinase Type 1Cell Line, TumorChromosomal InstabilityChromosomes, Artificial, HumanChromosomes, HumanGuanine Nucleotide Exchange FactorsHumansInterleukin-1 Receptor-Associated KinasesMitosisProtein KinasesProtein Serine-Threonine KinasesPTEN-Induced Putative KinaseRNA, Double-StrandedRNA, Small InterferingTransgenesCalcium-Calmodulin-Dependent Protein Kinase Type 1Guanine Nucleotide Exchange FactorsInterleukin-1 Receptor-Associated KinasesIRAK1 protein, humanPNCK protein, humanProtein KinasesProtein Serine-Threonine KinasesPTEN-Induced Putative KinaseRNA, Double-StrandedRNA, Small InterferingTRIO protein, human

Identifiers

PMID31515286
PMCPMC6771407
OpenAlexW2972906629

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.