Evidence map›Paper›PMID 31515257›Full record

ArticleCancer immunology research2019

Arash Nanbakhsh, Anupallavi Srinivasamani, Sandra Holzhauer, Matthew J Riese, Yongwei Zheng, Demin Wang, Robert Burns, Michael H Reimer, Sridhar Rao, Angela Lemke and 6 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancer immunology research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Article
  6. Research (Washington, D.C.) · 2023
    Article
  7. Review
  8. Review
  9. Article
  10. Review
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 3 institutions in 1 country.

Arash NanbakhshLaboratory of Molecular Immunology and Immunotherapy, Blood Research Institute, BloodCenter of Wisconsin, Milwaukee, Wisconsin.
Anupallavi SrinivasamaniLaboratory of Molecular Immunology and Immunotherapy, Blood Research Institute, BloodCenter of Wisconsin, Milwaukee, Wisconsin.
Sandra HolzhauerLaboratory of Lymphocyte Signaling, Blood Research Institute, BloodCenter of Wisconsin, Milwaukee, Wisconsin.
Matthew J RieseLaboratory of Lymphocyte Signaling, Blood Research Institute, BloodCenter of Wisconsin, Milwaukee, Wisconsin.
Yongwei ZhengLaboratory of B Cell Biology, Blood Research Institute, BloodCenter of Wisconsin, Milwaukee, Wisconsin.
Demin WangDepartment of Microbiology and Immunology, Medical College of Wisconsin, Milwaukee, Wisconsin.
Robert BurnsBioinformatics Core, Blood Research Institute, BloodCenter of Wisconsin, Milwaukee, Wisconsin.
Michael H ReimerLaboratory of Stem Cell Biology, Blood Research Institute, BloodCenter of Wisconsin, Milwaukee, Wisconsin.
Sridhar RaoLaboratory of Stem Cell Biology, Blood Research Institute, BloodCenter of Wisconsin, Milwaukee, Wisconsin.ORCID 0000-0003-2688-9541
Angela LemkeGenome Sciences and Precision Medicine Center, Medical College of Wisconsin, Milwaukee, Wisconsin.
Shirng-Wern TsaihGenome Sciences and Precision Medicine Center, Medical College of Wisconsin, Milwaukee, Wisconsin.ORCID 0000-0002-9836-4659
Michael J FlisterGenome Sciences and Precision Medicine Center, Medical College of Wisconsin, Milwaukee, Wisconsin.ORCID 0000-0001-8030-7739
Shunhua LaoLaboratory of Molecular Immunology and Immunotherapy, Blood Research Institute, BloodCenter of Wisconsin, Milwaukee, Wisconsin.
Richard DahlIndiana University School of Medicine, South Bend, Indiana.
Monica S ThakarLaboratory of Molecular Immunology and Immunotherapy, Blood Research Institute, BloodCenter of Wisconsin, Milwaukee, Wisconsin.
Subramaniam MalarkannanLaboratory of Molecular Immunology and Immunotherapy, Blood Research Institute, BloodCenter of Wisconsin, Milwaukee, Wisconsin. Subra.malar@bcw.edu.ORCID 0000-0002-7511-2731
Medical College of Wisconsin · USVersiti Blood Center of Wisconsin · USIndiana University South Bend · US

Funding

Cohesin Mutations in Acute Myelogenous LeukemiaR01CA204231 · NCI · VERSITI WISCONSIN, INC. · PI RAO, SRIDHAR · 2017 to 2021
$1.9M
Molecular signature of inflammationR01CA179363 · NCI · MEDICAL COLLEGE OF WISCONSIN · PI MALARKANNAN, SUBRAMANIAM · 2014 to 2018
$1.6M
Molecular mechanisms of signaling co-ordination in innate lymphocytesR01AI102893 · NIAID · MEDICAL COLLEGE OF WISCONSIN · PI MALARKANNAN, SUBRAMANIAM · 2013 to 2016
$1.5M
Fine-tuning of Hematopoiesis by the Mirn23a/b MiRNA ClustersR01DK109051 · NIDDK · INDIANA UNIVERSITY INDIANAPOLIS · PI DAHL, RICHARD E · 2016 to 2018
$847k
NCI NIH HHS R01 CA179363NCI NIH HHS R01 CA204231NIAID NIH HHS R01 AI102893NIDDK NIH HHS R01 DK109051
6 · The paper itself

Abstract

Natural killer (NK) cells generate proinflammatory cytokines that are required to contain infections and tumor growth. However, the posttranscriptional mechanisms that regulate NK cell functions are not fully understood. Here, we define the role of the microRNA cluster known as

Indexed as

AnimalsCells, CulturedCytokinesFemaleHumansInflammationKiller Cells, NaturalMaleMelanoma, ExperimentalMiceMice, Inbred C57BLMice, KnockoutMicroRNAsSignal TransductionT-Lymphocytes, CytotoxicTNF Receptor-Associated Factor 6CytokinesMicroRNAsMirn23b microRNA, mouseMirn24 microRNA, mouseMirn27 microRNA, mouseRela protein, mouseTNF Receptor-Associated Factor 6TRAF6 protein, mouseTranscription Factor AP-1Transcription Factor RelAUbiquitin

Identifiers

PMID31515257
PMCPMC7428857
OpenAlexW2972750808

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.