Evidence map›Paper›PMID 31514976›Full record

ReviewTrends in neurosciences2019

The Cortical Physiology of Ipsilateral Limb Movements.

David T Bundy, Eric C Leuthardt

Abstract readReview
In one paragraph

Review in Trends in neurosciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed.

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  16. Betz cells of the primary motor cortex.The Journal of comparative neurology · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

David T BundyDepartment of Rehabilitation Medicine, University of Kansas Medical Center, Kansas City, KS, USA; Department of Biomedical Engineering, Washington University, St. Louis, MO, USA.
Eric C LeuthardtDepartment of Biomedical Engineering, Washington University, St. Louis, MO, USA; Department of Neurological Surgery, Washington University, St. Louis, MO, USA; Center of Innovation in Neuroscience and Technology, Washington University, St. Louis, MO, USA. Electronic address: leuthardte@wustl.edu.

Funding

WU INSTITUTE OF CLINICAL AND TRANSLATIONAL SCIENCESUL1TR002345 · NCATS · WASHINGTON UNIVERSITY · PI William G. Powderly · 2017 to 2026
$97.8M
Washington University Institute of Clinical and Translational SciencesUL1TR000448 · NCATS · WASHINGTON UNIVERSITY · PI EVANOFF, BRADLEY A · 2012 to 2016
$41.4M
Development of a Micro-ECoG Neuroprosthesis for Motor Rehabilitation in a Chronic Corticospinal Stroke InjuryR01NS101013 · NINDS · WASHINGTON UNIVERSITY · PI LEUTHARDT, ERIC CLAUDE, MORAN, DANIEL WILLIAM · 2018 to 2022
$2.9M
Washington University Institute of Clinical and Translational SciencesTL1TR000449 · NCATS · WASHINGTON UNIVERSITY · PI EVANOFF, BRADLEY A · 2012 to 2016
$2.5M
The Neural Mechanisms of a Contralesionally-Driven Brain Computer Interface for Motor Rehabilitation of Chronic StrokeR21NS102696 · NINDS · WASHINGTON UNIVERSITY · PI CARTER, ALEXANDRE R, LEUTHARDT, ERIC CLAUDE · 2018 to 2019
$419k
LFP-Driven Activity-Dependent Stimulation Techniques for Acquired Brain InjuryF32NS100339 · NINDS · UNIVERSITY OF KANSAS MEDICAL CENTER · PI BUNDY, DAVID THOMAS · 2017 to 2019
$185k
NCATS NIH HHS TL1 TR000449NCATS NIH HHS UL1 TR000448NCATS NIH HHS UL1 TR002345NINDS NIH HHS F32 NS100339NINDS NIH HHS R01 NS101013NINDS NIH HHS R21 NS102696
6 · The paper itself

Abstract

Whereas voluntary movements have long been understood to derive primarily from the cortical hemisphere contralateral to a moving limb, substantial cortical activations also occur in the same-sided, or ipsilateral, cortical hemisphere. These ipsilateral motor activations have recently been shown to be useful to decode specific movement features. Furthermore, in contrast to the classical understanding that unilateral limb movements are solely driven by the contralateral hemisphere, it appears that the ipsilateral hemisphere plays an active and specific role in the planning and execution of voluntary movements. Here we review the movement-related activations observed in the ipsilateral cortical hemisphere, interpret this evidence in light of the potential roles of the ipsilateral hemisphere in the planning and execution of movements, and describe the implications for clinical populations.

Indexed as

MovementAnimalsBiomechanical PhenomenaExtremitiesFunctional LateralityHumansModels, NeurologicalMotor ActivityMotor CortexNeuronsPsychomotor Performancebimanual coordinationipsilateralmotor controlvoluntary movement

Identifiers

PMID31514976
PMCPMC6825896

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.