Evidence map›Paper›PMID 31514740›Full record

ArticleMalaria journal2019

Increasing trends of malaria in a border area of the Greater Mekong Subregion.

Jinting Geng, Pallavi Malla, Jiaqi Zhang, Shiling Xu, Cuiying Li, Yan Zhao, Qinghui Wang, Myat Phone Kyaw, Yaming Cao, Zhaoqing Yang and 1 more

Open access · goldAbstract read
In one paragraph

Article in Malaria journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 2 pooled it
11.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 2 syntheses or guidelines pooled it, 75 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Epidemiology of malaria and leishmaniasis in Thailand (2004-2025): A systematic review.Current research in parasitology & vector-borne diseases · 2026
    Review
  5. Efficacy of Primaquine for the Radical Cure of Plasmodium vivax Malaria in Northeast Myanmar and the Impact of Cytochrome P450 2D6 Genotypes.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2025
    Article
  6. Article
  7. Mapping residual malaria transmission in Vietnam.The Lancet regional health. Western Pacific · 2025
    Article
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  10. Observational
  11. Review
  12. Article
  13. Article
  14. Article
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  16. Different In Vitro Drug Susceptibility Profile ofTropical medicine and infectious disease · 2022
    Article
  17. PvMSP-3α and PvMSP-3β genotyping reveals higher genetic diversity in Plasmodium vivax parasites from migrant workers than residents at the China-Myanmar border.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2022
    Article
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  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Jinting GengDepartment of Pathogen Biology and Immunology, Kunming Medical University, Kunming, China.
Pallavi MallaDivision of Infectious Diseases and International Medicine, Department of Internal Medicine, Morsani College of Medicine, University of South Florida, 3720 Spectrum Boulevard, Suite 304, Tampa, FL, 33612, USA.
Jiaqi ZhangDepartment of Pathogen Biology and Immunology, Kunming Medical University, Kunming, China.
Shiling XuDepartment of Pathogen Biology and Immunology, Kunming Medical University, Kunming, China.
Cuiying LiDepartment of Pathogen Biology and Immunology, Kunming Medical University, Kunming, China.
Yan ZhaoDepartment of Immunology, College of Basic Medical Sciences, China Medical University, Shenyang, 110122, Liaoning, China.
Qinghui WangDepartment of Immunology, College of Basic Medical Sciences, China Medical University, Shenyang, 110122, Liaoning, China.
Myat Phone KyawMyanmar Medical Association, Yangon, Myanmar.
Yaming CaoDepartment of Immunology, College of Basic Medical Sciences, China Medical University, Shenyang, 110122, Liaoning, China.
Zhaoqing YangDepartment of Pathogen Biology and Immunology, Kunming Medical University, Kunming, China. zhaoqingy92@hotmail.com.
Liwang CuiDivision of Infectious Diseases and International Medicine, Department of Internal Medicine, Morsani College of Medicine, University of South Florida, 3720 Spectrum Boulevard, Suite 304, Tampa, FL, 33612, USA. lcui@health.usf.edu.ORCID http://orcid.org/0000-0002-8338-1974
Kunming Medical University · CNChina Medical University · CNUniversity of South Florida · US

Funding

Southeast Asia Malaria Research CenterU19AI089672 · NIAID · UNIVERSITY OF SOUTH FLORIDA · PI CUI, LIWANG · 2010 to 2023
$28.9M
National Natural Science Foundation of China 31260508National Natural Science Foundation of China U1202226NIAID NIH HHS U19 AI089672NIH HHS U19AI089672
6 · The paper itself

Abstract

backgroundIntensive malaria transmission along international borders is a significant impediment to malaria elimination in the Greater Mekong Subregion (GMS) of Southeast Asia. Passive case detection (PCD) was used to study the dynamics and trends of malaria transmission at the China-Myanmar border to provide epidemiologic information for improved malaria control.

methodsPCD was conducted in one hospital and 12 clinics near the Laiza town in northeast Myanmar from 2011 to 2016. Clinical malaria was diagnosed by microscopy and demographic information was captured using a structured questionnaire at the time of the patient's presentation for care.

resultsOver the study period, 6175 (19.7%) malaria cases were confirmed by microscopy from 31,326 suspected cases. The four human malaria parasite species were all identified, with Plasmodium vivax and Plasmodium falciparum accounting for 5607 (90.8%) and 481 (7.8%) of the confirmed cases, respectively. In contrast to the steady decline of malaria in the general GMS, the study site had an upward trend of malaria incidence with vivax malaria outbreaks in 2013 and 2016. Adult males, children under the age of 15, and those with occupations such as farming, being a soldier or student, had significantly higher risks of clinical malaria compared to having fevers from other aetiologies. A self-reported history of clinical malaria was also associated with a higher risk of confirmed malaria.

conclusionsThe China-Myanmar border area has experienced an overall upward trend of malaria incidence in recent years with P. vivax becoming the predominant species. Evidence-based control strategies need to focus on high-risk populations.

Indexed as

Socioeconomic FactorsAdolescentAdultAgedAged, 80 and overChildChild, PreschoolFemaleHumansIncidenceInfantInfant, NewbornMalariaMaleMiddle AgedMyanmarChina–Myanmar borderEliminationMalariaP. vivaxRisk factors

Identifiers

PMID31514740
PMCPMC6739967
OpenAlexW2972381870

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.