Evidence map›Paper›PMID 31514419›Full record

ArticleInternational journal of molecular sciences2019

Cooperativity and Steep Voltage Dependence in a Bacterial Channel.

Shang H Lin, Kai-Ti Chang, Nuval Cherian, Benjamin Wu, Hyo Phee, Christy Cho, Marco Colombini

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Triplin: Mechanistic Basis for Voltage Gating.International journal of molecular sciences · 2023
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Shang H LinDepartment of Biology, University of Maryland, College Park, MD 20742, USA.
Kai-Ti ChangDepartment of Biology, University of Maryland, College Park, MD 20742, USA.
Nuval CherianDepartment of Biology, University of Maryland, College Park, MD 20742, USA.
Benjamin WuDepartment of Biology, University of Maryland, College Park, MD 20742, USA.
Hyo PheeDepartment of Biology, University of Maryland, College Park, MD 20742, USA.
Christy ChoDepartment of Biology, University of Maryland, College Park, MD 20742, USA.
Marco ColombiniDepartment of Biology, University of Maryland, College Park, MD 20742, USA. colombini@umd.edu.

Funding

National Science Foundation MCB-1023008
6 · The paper itself

Abstract

This paper reports on the discovery of a novel three-membrane channel unit exhibiting very steep voltage dependence and strong cooperative behavior. It was reconstituted into planar phospholipid membranes formed by the monolayer method and studied under voltage-clamp conditions. The behavior of the novel channel-former, isolated from

Indexed as

ElectricityEscherichia coliIon Channel GatingIon ChannelsKineticsModels, BiologicalPorinsIon ChannelsPorinsdipoleelectrophysiologyEscherichia coliplanar membraneporevoltage gating

Identifiers

PMID31514419
PMCPMC6770917

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.