Evidence map›Paper›PMID 31514298›Full record

ReviewAntioxidants (Basel, Switzerland)2019

Zeaxanthin: Metabolism, Properties, and Antioxidant Protection of Eyes, Heart, Liver, and Skin.

Ana Gabriela Murillo, Siqi Hu, Maria Luz Fernandez

Open access · goldAbstract readReview
In one paragraph

Review in Antioxidants (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed, 2 pooled it
3.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 2 syntheses or guidelines pooled it, 116 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Journal of microbiology and biotechnology · 2026
    Article
  5. Article
  6. Review
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  12. Article
  13. Zeaxanthin augments CD8Cell reports. Medicine · 2025
    Article
  14. Review
  15. Nutrients and Bioactive Compounds fromInternational journal of molecular sciences · 2025
    Review
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  17. Review
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 2 countries.

Ana Gabriela MurilloBiochemistry Department, University of Costa Rica, San Pedro de Montes de Oca 2060, Costa Rica. gmurillo.nutricion@gmail.com.
Siqi HuDepartment of Nutritional Sciences, University of Connecticut, Storrs, CT 06269, USA. siqi.hu@uconn.edu.
Maria Luz FernandezDepartment of Nutritional Sciences, University of Connecticut, Storrs, CT 06269, USA. maria-luz.fernandez@uconn.edu.ORCID 0000-0002-1835-0792
University of Connecticut · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Zeaxanthin, a non-provitamin A carotenoid that belongs to the xanthophyll family, has been less studied than its isomer lutein. However, zeaxanthin has also been shown to have a number of beneficial effects for human health due to its ability to quench free radicals, exert antioxidant effects, as well as decrease inflammation. It is the purpose of this review to discuss the metabolism of zeaxanthin, including digestion, absorption, transport, and uptake by tissues, as well as the dietary or other factors which affect zeaxanthin bioavailability. In addition, this review also focuses on specific effects of this carotenoid on eye, skin, liver, and cardiovascular health. Data derived from human interventions, animal models of research, and in vitro and cell studies are discussed in this review.

Indexed as

age-related macular degenerationantioxidantatherosclerosisbioavailabilityinflammationliver healthtransportzeaxanthin

Identifiers

PMID31514298
PMCPMC6770730
OpenAlexW2972335534

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.