Evidence map›Paper›PMID 31514273›Full record

ReviewViruses2019

To Go or Stay: The Development, Benefit, and Detriment of Tissue-Resident Memory CD8 T Cells during Central Nervous System Viral Infections.

Taryn E Mockus, Heather M Ren, Shwetank, Aron E Lukacher

Abstract readReview
In one paragraph

Review in Viruses, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. CD8Frontiers in immunology · 2026
    Review
  2. Review
  3. Article
  4. Review
  5. Review
  6. Review
  7. Memory CD8Immunology · 2021
    Article
  8. Article
  9. Article
  10. Review
  11. Conditional Silencing of H-2DJournal of immunology (Baltimore, Md. : 1950) · 2020
    Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Taryn E MockusDepartment of Neurology, Ohio State University Wexner Medical Center, Columbus, OH 43210, USA.
Heather M RenDepartment of Microbiology and Immunology, Pennsylvania State University College of Medicine, Hershey, PA 17033, USA.
ShwetankBiocon Bristol-Myers Squib Research and Development Center, Biocon Park, Bengaluru 560099, India.
Aron E LukacherDepartment of Microbiology and Immunology, Pennsylvania State University College of Medicine, Hershey, PA 17033, USA. alukacher@pennstatehealth.psu.edu.ORCID 0000-0002-7969-2841

Funding

A Mouse Model to Define Immunovirologic Determinants of Polyomavirus CNS DiseaseR01NS088367 · NINDS · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI LUKACHER, ARON ELIOT · 2014 to 2021
$2.8M
Pathogenesis of Mouse Polyomavirus-associated CNS DemyelinationR01NS092662 · NINDS · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI LUKACHER, ARON ELIOT · 2016 to 2022
$2.1M
NINDS NIH HHS R01 NS088367NINDS NIH HHS R01 NS092662
6 · The paper itself

Abstract

CD8 T cells coordinate immune defenses against viral infections of the central nervous system (CNS). Virus-specific CD8 T cells infiltrate the CNS and differentiate into brain-resident memory CD8 T cells (CD8 bT

Indexed as

Immunologic MemoryAnimalsBrainCD8-Positive T-LymphocytesCentral Nervous System Viral DiseasesHumansCD8 T cellscentral nervous systemresident memory T cellsviral infection

Identifiers

PMID31514273
PMCPMC6784233

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.