ArticleThe Journal of allergy and clinical immunology2020
Investigation of the relationship between IL-6 and type 2 biomarkers in patients with severe asthma.
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Article in The Journal of allergy and clinical immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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0cells of the map it votes in
32citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
32 citing papers in PubMed, 64 citations in OpenAlex.
- Dupilumab Efficacy in Patients with Type 2 Asthma with and without Elevated Blood Neutrophils.Journal of immunology research · 2023Trial
- Different Inflammatory Phenotypes and Immune Endotypes Drive Disease Heterogeneity in Asthma and COPD.Clinical reviews in allergy & immunology · 2026Review
- Systemic-airway eosinophil discordance and sputum mediator profiling in severe asthma treated with biologics: a retrospective cohort study.BMC pulmonary medicine · 2026Article
- The central role of IL-6 in the differential effects of GLP-1 receptor agonists and metformin across multiple health conditions.Frontiers in immunology · 2026Review
- Bidirectional causal association and shared anti-inflammatory target of asthma and atopic dermatitis: a Mendelian randomization and colocalisation study.BMC pulmonary medicine · 2025Article
- Impact of clinical factors and season on inflammatory cytokines in biologic-treated and untreated asthma.Respiratory research · 2025Article
- Unraveling the mechanisms of virus-induced asthma exacerbation: epithelial injury, immune dysregulation, and novel interventions.Chinese medical journal pulmonary and critical care medicine · 2025Review
- Circadian Clock Disruption and Non-type 2 Asthma: A Hypothesis-Driven Perspective on Immune, Epithelial, and Steroid Response.Clinical reviews in allergy & immunology · 2025Review
- The role of type 2 diabetes in the severity of adult asthma.Current opinion in allergy and clinical immunology · 2025Review
- Investigation of lactotransferrin messenger RNA expression levels as an anti-type 2 asthma biomarker.The Journal of allergy and clinical immunology · 2024Article
- Advances in non-type 2 severe asthma: from molecular insights to novel treatment strategies.The European respiratory journal · 2024Review
- Circulating Biomarkers, Fraction of Exhaled Nitric Oxide, and Lung Function in Patients With Human Immunodeficiency Virus and Tuberculosis.The Journal of infectious diseases · 2024Article
- Investigations of a combination of atopic status and age of asthma onset identify asthma subphenotypes.The Journal of asthma : official journal of the Association for the Care of Asthma · 2023Article
- Genetic analyses of chr11p15.5 region identifyThe Journal of asthma : official journal of the Association for the Care of Asthma · 2023Article
- Genomics of Treatable Traits in Asthma.Genes · 2023Review
- Phenotype overlap in the natural history of asthma.European respiratory review : an official journal of the European Respiratory Society · 2023Review
- Low CC16 mRNA Expression Levels in Bronchial Epithelial Cells Are Associated with Asthma Severity.American journal of respiratory and critical care medicine · 2023Article
- Systemic corticosteroids in asthma: A call to action from World Allergy Organization and Respiratory Effectiveness Group.The World Allergy Organization journal · 2022Review
- The Impact of Insulin Resistance on Loss of Lung Function and Response to Treatment in Asthma.American journal of respiratory and critical care medicine · 2022Article
- Interleukin-6 promotes ferroptosis in bronchial epithelial cells by inducing reactive oxygen species-dependent lipid peroxidation and disrupting iron homeostasis.Bioengineered · 2021Article
Corrections and comments
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Authors and funding
19 authors at 10 institutions in 1 country.
Xingnan LiDivision of Genetics, Genomics and Precision Medicine, Department of Medicine, University of Arizona, Tucson, Ariz. Electronic address: lixingnan1@deptofmed.arizona.edu.
Annette T HastieDepartment of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, NC.
Michael C PetersDivision of Pulmonary and Critical Care Medicine, Department of Medicine, University of California at San Francisco, San Francisco, Calif.
Gregory A HawkinsDepartment of Biochemistry, Wake Forest School of Medicine, Winston-Salem, NC.
Wanda PhipatanakulBoston Children's Hospital, Boston, Mass; Division of Allergy and Immunology, Harvard Medical School, Boston, Mass.
Huashi LiDivision of Genetics, Genomics and Precision Medicine, Department of Medicine, University of Arizona, Tucson, Ariz.
Wendy C MooreDepartment of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, NC.
William W BusseDepartment of Medicine, University of Wisconsin School of Medicine, Madison, Wis.
Mario CastroDivision of Pulmonary and Critical Care Medicine, Washington University School of Medicine, St Louis, Mo.
Serpil C ErzurumLerner Research Institute, Cleveland, Ohio.
Benjamin GastonDivision of Pediatric Pulmonology, Rainbow Babies and Children's Hospital and Cleveland Medical Center, Cleveland, Ohio.
Elliot IsraelDivision of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Mass.
Nizar N JarjourDepartment of Medicine, University of Wisconsin School of Medicine, Madison, Wis.
Bruce D LevyDivision of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Mass.
Sally E WenzelDepartment of Environmental and Occupational Health, University of Pittsburgh, Pittsburgh, Pa.
Deborah A MeyersDivision of Genetics, Genomics and Precision Medicine, Department of Medicine, University of Arizona, Tucson, Ariz.
John V FahyDivision of Pulmonary and Critical Care Medicine, Department of Medicine, University of California at San Francisco, San Francisco, Calif.
Eugene R BleeckerDivision of Genetics, Genomics and Precision Medicine, Department of Medicine, University of Arizona, Tucson, Ariz.
National Heart, Lung, and Blood Institute's Severe Asthma Research Program (SARP) Networks
University of Arizona · USWake Forest University · USBrigham and Women's Hospital · USUniversity of California, San Francisco · USUniversity of Wisconsin–Madison · USBoston Children's Hospital · USCleveland Clinic Lerner College of Medicine · USRainbow Babies & Children's Hospital · USUniversity of Pittsburgh · USWashington University in St. Louis · US
Funding
WU INSTITUTE OF CLINICAL AND TRANSLATIONAL SCIENCESUL1TR002345 · NCATS · WASHINGTON UNIVERSITY · PI William G. Powderly · 2017 to 2026
$97.8MWashington University Institute of Clinical and Translational Sciences (UL1)UL1RR024992 · NCRR · WASHINGTON UNIVERSITY · PI EVANOFF, BRADLEY A · 2007 to 2011
$45.4MWORKER PROTECTION AGAINST AIRBORNE INFLUENZA - A PILOT STUDYM01RR007122 · NCRR · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI HOLMES, ROSS P · 1992 to 2010
$35.2MZOSUQUIDAR TRIHYDROCHLORIDE IN NEWLY DIAGNOSED AMLM01RR003186 · NCRR · UNIVERSITY OF WISCONSIN-MADISON · PI MATLOUB, YOUSIF H · 1986 to 2007
$19.3MRapid saliva antigen test for SARS-CoV-2 detectionU01HL146002 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI ARONICA, MARK A, CASTRO, MARIO · 2019 to 2023
$17.3MVIRALLY-INDUCED STAT-1, STAT-3 AND STAT-6M01RR018390 · NCRR · CLEVELAND CLINIC LERNER COM-CWRU · PI GILDEA, THOMAS · 2003 to 2007
$11.0MSevere Asthma Research ProjectR01HL069174 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI WENZEL, SALLY E · 2001 to 2010
$9.2MClinical Coordinating Center for the Severe Asthma Research Program (SARP)U10HL109086 · NHLBI · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI MAUGER, DAVID T. · 2011 to 2017
$8.1MGenome Wide Association for Asthma and Lung FunctionR01HL087665 · NHLBI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI MEYERS, DEBORAH A. · 2007 to 2009
$7.7MSevere Asthma From Respiratory InfectionsR01HL069116 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI BUSSE, WILLIAM W. · 2001 to 2010
$7.6MGenotype-Phenotype Interactions in Severe AsthmaR01HL069167 · NHLBI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI BLEECKER, EUGENE ROLAND · 2001 to 2010
$5.5MRedox Determinants of Severe AsthmaR01HL069170 · NHLBI · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI ERZURUM, SERPIL C. · 2001 to 2010
$5.1MNCATS NIH HHS UL1 TR002345NCRR NIH HHS M01 RR003186NCRR NIH HHS M01 RR007122NCRR NIH HHS M01 RR018390NCRR NIH HHS UL1 RR024992NHLBI NIH HHS R01 HL069116NHLBI NIH HHS R01 HL069130NHLBI NIH HHS R01 HL069149NHLBI NIH HHS R01 HL069155NHLBI NIH HHS R01 HL069167NHLBI NIH HHS R01 HL069170NHLBI NIH HHS R01 HL069174NHLBI NIH HHS R01 HL069349NHLBI NIH HHS R01 HL087665NHLBI NIH HHS R01 HL091762NHLBI NIH HHS R01 HL122531NHLBI NIH HHS U10 HL109086NHLBI NIH HHS U10 HL109152NHLBI NIH HHS U10 HL109164NHLBI NIH HHS U10 HL109168NHLBI NIH HHS U10 HL109172NHLBI NIH HHS U10 HL109250NHLBI NIH HHS U10 HL109257
Abstract
PubMed holds no abstract for this paper.
Indexed as
AdolescentAdultAsthmaBiomarkersChildFemaleHumansInterleukin-6MaleSeverity of Illness IndexBiomarkersIL6 protein, humanInterleukin-6
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.