Impact of specimen storage temperature and time on the implementation of GeneXpert® testing for sexually transmitted infections in resource-constraint settings.

Liteboho D Maduna, Marleen M Kock, Andrew Medina-Marino, Jeffrey D Klausner, Remco P H Peters

Abstract read

In one paragraph

Article in Journal of microbiological methods, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Point-by-Point Progress: Gonorrhea Point of Care Tests.Expert review of molecular diagnostics · 2020
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Liteboho D MadunaDepartment of Medical Microbiology, University of Pretoria, Pretoria, South Africa.

Marleen M KockDepartment of Medical Microbiology, University of Pretoria, Pretoria, South Africa; Tshwane Academic Division, National Health Laboratory Service, Pretoria, South Africa.

Andrew Medina-MarinoResearch Unit, Foundation for Professional Development, Pretoria, South Africa.

Jeffrey D KlausnerDavid Geffen School of Medicine, University of California-Los Angeles, Los Angeles, CA, USA; Department of Epidemiology, National Health Laboratory Services, University of California-Los Angeles, Los Angeles, CA, USA.

Remco P H PetersDepartment of Medical Microbiology, University of Pretoria, Pretoria, South Africa; Anova Health Institute, Johannesburg, South Africa; Department of Medical Microbiology, School of Public Health & Primary Care (CAPHRI), Maastricht University Medical Centre, Maastricht, The Netherlands. Electronic address: rph.peters@gmail.com.

Funding

Pilot Study of STI Screening and Treatment for PMTCTR21HD084274 · NICHD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI KLAUSNER, JEFFREY DAVID, MEDINA-MARINO, ANDREW · 2015 to 2016

$352k

NICHD NIH HHS R21 HD084274

6 · The paper itself

Abstract

Implementation of routine laboratory diagnostics is imperative to address the high burden of sexually transmitted infections (STI) in Sub-Saharan Africa. We demonstrate that logistical challenges of specimen storage, temperature and transport time are unlikely to impact on performance of routine STI diagnostics using the GeneXpert® platform implemented in these settings.

Indexed as

Africa South of the SaharaChlamydia trachomatisFemaleHumansNeisseria gonorrhoeaeSexually Transmitted Diseases, BacterialSpecimen HandlingTemperatureTrichomonas vaginalisUrine

Identifiers

PMID31513857

DOI10.1016/j.mimet.2019.105719

PMCPMC6885606

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.