Evidence map›Paper›PMID 31513654›Full record

ArticlePloS one2019

Genomic characterization of the complete terpene synthase gene family from Cannabis sativa.

Keith D Allen, Kevin McKernan, Christopher Pauli, Jim Roe, Anthony Torres, Reggie Gaudino

Abstract read
In one paragraph

Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

  1. Article
  2. Review
  3. Exploring Aroma and Flavor Diversity inMolecules (Basel, Switzerland) · 2025
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Terpenes and Cannabinoids in Supercritical COPharmaceuticals (Basel, Switzerland) · 2022
    Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Keith D AllenSteep Hill Labs, Berkeley, California, United States of America.ORCID 0000-0003-0752-4141
Kevin McKernanMedicinal Genomics, Woburn, Massachusetts, United States of America.ORCID 0000-0002-3908-1122
Christopher PauliSteep Hill Labs, Berkeley, California, United States of America.
Jim RoeSteep Hill Labs, Berkeley, California, United States of America.
Anthony TorresSteep Hill Labs, Berkeley, California, United States of America.
Reggie GaudinoSteep Hill Labs, Berkeley, California, United States of America.ORCID 0000-0001-5902-5606

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Terpenes are responsible for most or all of the odor and flavor properties of Cannabis sativa, and may also impact effects users experience either directly or indirectly. We report the diversity of terpene profiles across samples bound for the Washington dispensary market. The remarkable degree of variation in terpene profiles ultimately results from action of a family of terpene synthase genes, only some of which have been described. Using a recently available genome assembly we describe 55 terpene synthases with genomic context, and tissue specific expression. The family is quite diverse from a protein similarity perspective, and subsets of the family are expressed in all tissues in the plant, including a set of root specific monoterpene synthases that could well have agronomic importance. Ultimately understanding and breeding for specific terpene profiles will require a good understanding of the gene family that underlies it. We intend for this work to serve as a foundation for that.

Indexed as

Alkyl and Aryl TransferasesCannabisCloning, MolecularEvolution, MolecularFlowersGenes, PlantGenome, PlantGenomicsPhylogenyTerpenesAlkyl and Aryl TransferasesTerpenesterpene synthase

Identifiers

PMID31513654
PMCPMC6742361

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.