Evidence map›Paper›PMID 31513590›Full record

ArticlePloS one2019

Impact of pterygium on the ocular surface and meibomian glands.

Ana Claudia Viana Wanzeler, Italo Antunes França Barbosa, Bruna Duarte, Eduardo Buzolin Barbosa, Daniel Almeida Borges, Monica Alves

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 25 citations in OpenAlex.

  1. Review
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  8. Article
  9. [Pterygium: pathogenesis, diagnosis and treatment].Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Ana Claudia Viana WanzelerDepartment of Ophthalmology, Faculty of Medical Sciences, University of Campinas-UNICAMP, Campinas, SP, Brazil.ORCID 0000-0003-3057-880X
Italo Antunes França BarbosaDepartment of Ophthalmology, Faculty of Medical Sciences, University of Campinas-UNICAMP, Campinas, SP, Brazil.
Bruna DuarteDepartment of Ophthalmology, Faculty of Medical Sciences, University of Campinas-UNICAMP, Campinas, SP, Brazil.
Eduardo Buzolin BarbosaDepartment of Ophthalmology, Faculty of Medical Sciences, University of Campinas-UNICAMP, Campinas, SP, Brazil.
Daniel Almeida BorgesDepartment of Ophthalmology, Faculty of Medical Sciences, University of Campinas-UNICAMP, Campinas, SP, Brazil.
Monica AlvesDepartment of Ophthalmology, Faculty of Medical Sciences, University of Campinas-UNICAMP, Campinas, SP, Brazil.
Universidade Estadual de Campinas (UNICAMP) · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo analyze how ocular surface parameters correlate to presence of pterygium and investigate the possible impact of pterygia on tear film findings and meibomian glands findings.

methodsWe investigated objective parameters of the ocular surface such as conjunctival hyperemia, tear film stability and volume, meibomian gland dysfunction, dry eye disease, corneal topography comparing healthy individuals and correlating with the pterygium clinical presentation.

resultsA total of 83 patients were included. Corneal astigmatism induction was 2.65 ± 2.52 D (0.4-11.8). The impact of pterygium on the ocular surface parameters compared to matched controls was seen in: conjunctival hyperemia (control 1.55±0.39/pterygium 2.14±0.69; p = 0.0001), tear meniscus height (control 0.24±0.05 mm/pterygium 0.36±0.14mm; p 0.0002), meiboscore lower eyelid (control 0.29±0.64/pterygium 1.38±0.95; p 0.0001) and meiboscore upper eyelid (control 0.53±0.62/pterygium 0.98±0.75; p = 0.0083). We found a high number of pterygium patients (88%) presented meibomian gland alterations. Interestingly, meibomian gland loss was coincident to the localization of the pterygium in 54% of the upper and 77% lower lids.

conclusionPterygium greatly impacts on ocular surface by inducing direct alterations in the pattern of meibomian glands besides corneal irregularities, conjunctival hyperemia and lacrimal film alterations, inducing significant symptoms and potential signs of dysfunction.

Indexed as

AdultAgedAnterior Eye SegmentCase-Control StudiesCorneal TopographyFemaleHumansMaleMeibomian GlandsMiddle AgedPterygiumSeverity of Illness Index

Identifiers

PMID31513590
PMCPMC6742459
OpenAlexW2972744090

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.