Evidence map›Paper›PMID 31513447›Full record

ArticleJournal of applied physiology (Bethesda, Md. : 1985)2019

Consistent expression pattern of myogenic regulatory factors in whole muscle and isolated human muscle satellite cells after eccentric contractions in humans.

Joshua P Nederveen, Stephen A Fortino, Jeff M Baker, Tim Snijders, Sophie Joanisse, Chris McGlory, Bryon R McKay, Dinesh Kumbhare, Gianni Parise

Open access · bronzeAbstract read
In one paragraph

Article in Journal of applied physiology (Bethesda, Md. : 1985), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 20 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Buffalo bbu-miR-493-5p Promotes Myoblast Proliferation and Differentiation.Animals : an open access journal from MDPI · 2024
    Article
  6. Molecular clocks, satellite cells, and skeletal muscle regeneration.American journal of physiology. Cell physiology · 2023
    Review
  7. Article
  8. Review
  9. Review
  10. Metabolic Health-The Role of Adipo-Myokines.International journal of molecular sciences · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Joshua P NederveenDepartment of Kinesiology, Maastricht University, Maastricht, The Netherlands.
Stephen A FortinoDepartment of Kinesiology, Maastricht University, Maastricht, The Netherlands.
Jeff M BakerDepartment of Kinesiology, Maastricht University, Maastricht, The Netherlands.
Tim SnijdersDepartment of Kinesiology, Maastricht University, Maastricht, The Netherlands.
Sophie JoanisseDepartment of Kinesiology, Maastricht University, Maastricht, The Netherlands.
Chris McGloryDepartment of Kinesiology, Maastricht University, Maastricht, The Netherlands.
Bryon R McKayDepartment of Kinesiology, Maastricht University, Maastricht, The Netherlands.
Dinesh KumbhareDepartment of Medicine, McMaster University, Hamilton, Ontario, Canada.
Gianni PariseDepartment of Kinesiology, Maastricht University, Maastricht, The Netherlands.
Maastricht University · NLMcMaster University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Skeletal muscle satellite cells (SC) play an important role in muscle repair following injury. The regulation of SC activity is governed by myogenic regulatory factors (MRF), including MyoD, Myf5, myogenin, and MRF4. The mRNA expression of these MRF in humans following muscle damage has been predominately measured in whole muscle homogenates. Whether the temporal expression of MRF in a whole muscle homogenate reflects SC-specific expression of MRF remains largely unknown. Sixteen young men (23.1 ± 1.0 yr) performed 300 unilateral eccentric contractions (180°/s) of the knee extensors. Percutaneous muscle biopsies from the vastus lateralis were taken before (Pre) and 48 h postexercise. Fluorescence-activated cell sorting analysis was utilized to purify NCAM

Indexed as

ExerciseGene ExpressionHumansMaleMuscle ContractionMuscle, SkeletalMyogenic Regulatory FactorsRNA, MessengerSatellite Cells, Skeletal MuscleYoung AdultMyogenic Regulatory FactorsRNA, Messengerfluorescence-activated cell sortingmRNA expressionmyogenic regulator factorssatellite cell

Identifiers

PMID31513447
PMCPMC6879834
OpenAlexW2972632674

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.