Evidence map›Paper›PMID 31513401›Full record

ArticleThe Journal of organic chemistry2019

Development of an Imine Chaperone for Selective C-H Functionalization of Alcohols via Radical Relay.

Kohki M Nakafuku, Raymond K Twumasi, Avassaya Vanitcha, Ethan A Wappes, Kayambu Namitharan, Mathieu Bekkaye, David A Nagib

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of organic chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.9field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 9 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Kohki M NakafukuDepartment of Chemistry and Biochemistry , The Ohio State University , Columbus , Ohio 43210 , United States.
Raymond K TwumasiDepartment of Chemistry and Biochemistry , The Ohio State University , Columbus , Ohio 43210 , United States.
Avassaya VanitchaDepartment of Chemistry and Biochemistry , The Ohio State University , Columbus , Ohio 43210 , United States.
Ethan A WappesDepartment of Chemistry and Biochemistry , The Ohio State University , Columbus , Ohio 43210 , United States.
Kayambu NamitharanDepartment of Chemistry and Biochemistry , The Ohio State University , Columbus , Ohio 43210 , United States.
Mathieu BekkayeDepartment of Chemistry and Biochemistry , The Ohio State University , Columbus , Ohio 43210 , United States.
David A NagibDepartment of Chemistry and Biochemistry , The Ohio State University , Columbus , Ohio 43210 , United States.ORCID 0000-0002-2275-6381
The Ohio State University · US

Funding

Radical Chaperones to Harness Remote, Selective C-H Functionalization MechanismsR35GM119812 · NIGMS · OHIO STATE UNIVERSITY · PI NAGIB, DAVID A · 2016 to 2025
$4.0M
A proposal for the purchase of a new Cu anode Microsource X-ray Diffractometer wiS10RR027172 · NCRR · UNIVERSITY OF CALIFORNIA BERKELEY · PI RAYMOND, KENNETH N · 2010 to 2010
$500k
NCRR NIH HHS S10 RR027172NIGMS NIH HHS R35 GM119812
6 · The paper itself

Abstract

The design of a radical relay chaperone to promote selective C-H functionalizations is described. A saccharin-based imine was found to be uniquely suited to effect C-H amination of alcohols via an

Indexed as

AlcoholsFree RadicalsIminesMolecular ChaperonesMolecular StructureAlcoholsFree RadicalsIminesMolecular Chaperones

Identifiers

PMID31513401
PMCPMC6948922
OpenAlexW2972475725

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.