ArticleMagnetic resonance in medicine2020
Quantification of cerebral perfusion and cerebrovascular reserve using Turbo-QUASAR arterial spin labeling MRI.
Article in Magnetic resonance in medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 3 of them syntheses that pooled it.
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Who cites it
15 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Research progress on the application of functional magnetic resonance imaging in cognitive dysfunction in patients with cerebral small vessel disease.Frontiers in neurology · 2025Pooled it
- Measuring Quantitative Cerebral Blood Flow in Healthy Children: A Systematic Review of Neuroimaging Techniques.Journal of magnetic resonance imaging : JMRI · 2024Pooled it
- Reproducibility of cerebrovascular reactivity measurements: A systematic review of neuroimaging techniquesJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2022Pooled it
- Perfusion Signal Analysis Using Multi-pulsed Arterial Spin Labeling (mPASL) with Multiple Post-labeling Delays: Phantom Validation and Application to the Human Foot.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2026Article
- Estimation of hypoperfused tissue volume in large vessel occlusions: pseudo-continuous arterial spin labeling versus dynamic susceptibility contrast perfusion-weighted imaging.Quantitative imaging in medicine and surgery · 2025Article
- Evaluating cerebrovascular reactivity measured by velocity selective inversion arterial spin labeling with different post-labeling delays: The effect of fast flow.Magnetic resonance in medicine · 2024Article
- Article
- Recommendations for quantitative cerebral perfusion MRI using multi-timepoint arterial spin labeling: Acquisition, quantification, and clinical applications.Magnetic resonance in medicine · 2024Review
- Revascularization improves vascular hemodynamics - a study assessing cerebrovascular reserve and transit time in Moyamoya patients using MRI.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2023Article
- Assessment of functional shunting in patients with sickle cell disease.Haematologica · 2022Article
- Velocity-selective arterial spin labeling perfusion MRI: A review of the state of the art and recommendations for clinical implementation.Magnetic resonance in medicine · 2022Review
- Using arterial spin labeling to measure cerebrovascular reactivity in Moyamoya disease: Insights from simultaneous PET/MRI.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2022Article
- Cerebrovascular reactivity measurements using simultaneousNeuroImage · 2021Article
- Animal model of assessing cerebrovascular functional reserve by imaging photoplethysmography.Scientific reports · 2020Article
- Quantification of cerebral perfusion and cerebrovascular reserve using Turbo-QUASAR arterial spin labeling MRI.Magnetic resonance in medicine · 2020Article
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9 authors.
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Abstract
purposeTo compare cerebral blood flow (CBF) and cerebrovascular reserve (CVR) quantification from Turbo-QUASAR (quantitative signal targeting with alternating radiofrequency labeling of arterial regions) arterial spin labeling (ASL) and single post-labeling delay pseudo-continuous ASL (PCASL).
methodsA model-based method was developed to quantify CBF and arterial transit time (ATT) from Turbo-QUASAR, including a correction for magnetization transfer effects caused by the repeated labeling pulses. Simulations were performed to assess the accuracy of the model-based method. Data from an in vivo experiment conducted on a healthy cohort were retrospectively analyzed to compare the CBF and CVR (induced by acetazolamide) measurement from Turbo-QUASAR and PCASL on the basis of global and regional differences. The quality of the two ASL data sets was examined using the coefficient of variation (CoV).
resultsThe model-based method for Turbo-QUASAR was accurate for CBF estimation (relative error was 8% for signal-to-noise ratio = 5) in simulations if the bolus duration was known. In the in vivo experiment, the mean global CVR estimated by Turbo-QUASAR and PCASL was between 63% and 64% and not significantly different. Although global CBF values of the two ASL techniques were not significantly different, regional CBF differences were found in deep gray matter in both pre- and postacetazolamide conditions. The CoV of Turbo-QUASAR data was significantly higher than PCASL.
conclusionBoth ASL techniques were effective for quantifying CBF and CVR, despite the regional differences observed. Although CBF estimated from Turbo-QUASAR demonstrated a higher variability than PCASL, Turbo-QUASAR offers the advantage of being able to measure and control for variation in ATT.
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