Evidence map›Paper›PMID 31513013›Full record

ArticleeLife2019

Neural stem cell temporal patterning and brain tumour growth rely on oxidative phosphorylation.

Jelle van den Ameele, Andrea H Brand

Open access · goldAbstract read
In one paragraph

Article in eLife, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 71 citations in OpenAlex.

  1. Article
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  7. Cell cycle-dependent cues regulate temporal patterning of thebioRxiv : the preprint server for biology · 2025
    Article
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  10. Review
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  13. Review
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  15. eLife · 2024
    Article
  16. Article
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  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Jelle van den AmeeleThe Gurdon Institute, Cambridge, United Kingdom.ORCID 0000-0002-2744-0810
Andrea H BrandThe Gurdon Institute, Cambridge, United Kingdom.ORCID 0000-0002-2089-6954
University of Cambridge · GB

Funding

Cancer Research UK C6946/A14492European Molecular Biology Organization ALTF 1600_2014Wellcome Trust 092096Wellcome Trust 103792Wellcome Trust 105839
6 · The paper itself

Abstract

Translating advances in cancer research to clinical applications requires better insight into the metabolism of normal cells and tumour cells in vivo. Much effort has focused on understanding how glycolysis and oxidative phosphorylation (OxPhos) support proliferation, while their impact on other aspects of development and tumourigenesis remain largely unexplored. We found that inhibition of OxPhos in neural stem cells (NSCs) or tumours in the

Indexed as

Cell ProliferationOxidative PhosphorylationAnimalsBrain NeoplasmsCell DifferentiationDisease Models, AnimalDrosophilaGlycolysisNeural Stem Cellsbrain tumoursdevelopmental biologyD. melanogasterneural stem cellsoxidative phosphorylationregenerative medicinestem cellstemporal patterningtumour heterogeneityWarburg effect

Identifiers

PMID31513013
PMCPMC6763261
OpenAlexW2972729573

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.