Evidence map›Paper›PMID 31512951›Full record

ArticleAmerican journal on intellectual and developmental disabilities2019

Positive Emotional Support in Premutation Carrier Mothers of Adolescents and Adults With Fragile X Syndrome: Gene by Environment Interactions.

Sigan L Hartley, Leann S DaWalt, Jinkuk Hong, Jan S Greenberg, Marsha R Mailick

Abstract read
In one paragraph

Article in American journal on intellectual and developmental disabilities, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Cognitive dysfunction in women with theJournal of Alzheimer's disease : JAD · 2026
    Article
  3. Article
  4. Depression Symptom Trajectories in Mothers With the FMR1 Premutation Vary by CGG Repeat Length: A Longitudinal Study of 73 Women Spanning 20-75 Years of Age.American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics · 2025
    Article
  5. Review
  6. Article
  7. Health Effects of Sleep Quality in Premutation Carrier Mothers of Individuals With Fragile X Syndrome.American journal on intellectual and developmental disabilities · 2023
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Sigan L HartleySigan L. Hartley, Waisman Center and School of Human Ecology, University of Wisconsin-Madison; Leann S. DaWalt, Jinkuk Hong, Jan S. Greenberg, and Marsha R. Mailick, Waisman Center, University of Wisconsin-Madison.
Leann S DaWaltSigan L. Hartley, Waisman Center and School of Human Ecology, University of Wisconsin-Madison; Leann S. DaWalt, Jinkuk Hong, Jan S. Greenberg, and Marsha R. Mailick, Waisman Center, University of Wisconsin-Madison.
Jinkuk HongSigan L. Hartley, Waisman Center and School of Human Ecology, University of Wisconsin-Madison; Leann S. DaWalt, Jinkuk Hong, Jan S. Greenberg, and Marsha R. Mailick, Waisman Center, University of Wisconsin-Madison.
Jan S GreenbergSigan L. Hartley, Waisman Center and School of Human Ecology, University of Wisconsin-Madison; Leann S. DaWalt, Jinkuk Hong, Jan S. Greenberg, and Marsha R. Mailick, Waisman Center, University of Wisconsin-Madison.
Marsha R MailickSigan L. Hartley, Waisman Center and School of Human Ecology, University of Wisconsin-Madison; Leann S. DaWalt, Jinkuk Hong, Jan S. Greenberg, and Marsha R. Mailick, Waisman Center, University of Wisconsin-Madison.
University of Wisconsin–Madison · US

Funding

UNC MRDD Research CenterP30HD003110 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BELGER, AYSENIL · 1985 to 2012
$28.7M
Waisman Intellectual and Developmental Disabilities Research Center Down Syndrome RegistryU54HD090256 · NICHD · UNIVERSITY OF WISCONSIN-MADISON · PI POLLAK, SETH D · 2016 to 2020
$6.0M
FMR1 Premutation Phenotypes in Population-Based & Clinically-Ascertained SamplesR01HD082110 · NICHD · UNIVERSITY OF WISCONSIN-MADISON · PI Leann Smith DaWalt, MARSHA RUTH MAILICK · 2015 to 2026
$5.1M
NICHD NIH HHS P30 HD003110NICHD NIH HHS R01 HD082110NICHD NIH HHS U54 HD090256
6 · The paper itself

Abstract

We examined the benefit of emotional support on daily health in premutation carrier mothers of adolescents and adults with fragile X syndrome (

Indexed as

Gene-Environment InteractionHealth StatusSocial SupportAdolescentAdultAgedFemaleFragile X Messenger Ribonucleoprotein 1Fragile X SyndromeHeterozygoteHumansMaleMiddle AgedMothersSelf ReportTrinucleotide RepeatsFMR1 protein, humanFragile X Messenger Ribonucleoprotein 1CGG repeatFMR1fragile X syndromehealthpermutationsupport

Identifiers

PMID31512951
PMCPMC6948144
OpenAlexW2972698198

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.