Evidence map›Paper›PMID 31512813›Full record

SynthesisThe Kaohsiung journal of medical sciences2020

Prognostic value of the C-reactive protein to albumin ratio in esophageal cancer: A systematic review and meta-analysis.

Yan Wang, Xu Hu, Yu Huang, Wen-Ying Xu, Yan-Ming Wu, Peng-Fei Li, Guo-Wei Che

Open access · goldAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in The Kaohsiung journal of medical sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 5 pooled it
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 5 syntheses or guidelines pooled it, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Yan WangDepartment of Thoracic Surgery, West China Hospital, Sichuan University, Chengdu, China.
Xu HuWest China School of Medicine, Sichuan University, Chengdu, China.
Yu HuangWest China School of Medicine, Sichuan University, Chengdu, China.
Wen-Ying XuWest China School of Medicine, Sichuan University, Chengdu, China.
Yan-Ming WuDepartment of Thoracic Surgery, West China Hospital, Sichuan University, Chengdu, China.
Peng-Fei LiDepartment of Thoracic Surgery, West China Hospital, Sichuan University, Chengdu, China.
Guo-Wei CheDepartment of Thoracic Surgery, West China Hospital, Sichuan University, Chengdu, China.ORCID https://orcid.org/0000-0003-2187-6346
Sichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent years, some studies suggested that the pretreatment C-reactive protein to albumin ratio (CAR) may be predictive for prognosis of esophageal cancer (EC), but their results were inconsistent. Therefore, the current meta-analysis was preformed to better determine the prognostic value of pretreatment CAR in EC. The PubMed, EMBASE, Web of Science, Cochrane Library, and PubMed Central databases were searched up to January 10, 2019 to identify studies evaluating the correlation between CAR and prognosis of EC. The primary outcome was the overall survival (OS) and secondary outcomes were disease-free survival (DFS) and cancer-specific survival (CSS). Pooled hazard ratios (HRs) and corresponding 95% confidence intervals (95% CIs) were used to estimate the predictive role of CAR for prognosis in EC. Based on the results of this research, a total of 11 studies with 2930 patients diagnosed as EC were included. Pooled results suggested that elevated pretreatment CAR was significantly associated with poor OS (HR = 1.80, 95% CI: 1.31-2.47, P < .001) with high heterogeneity (I

Indexed as

AnimalsC-Reactive ProteinDisease-Free SurvivalEsophageal NeoplasmsHumansPrognosisSerum AlbuminC-Reactive ProteinSerum AlbuminC-reactive protein to albumin ratioesophageal cancermeta-analysisprognosis

Identifiers

PMID31512813
PMCPMC11896523
OpenAlexW2973053352

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.