ArticleCurrent opinion in toxicology2019
Mechanisms of Chromium-Induced Toxicity.
Article in Current opinion in toxicology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 97 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
97 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Human Health Effects of Oral Exposure to Chromium: A Systematic Review of the Epidemiological Evidence.International journal of environmental research and public health · 2024Pooled it
- Assessment of Serum Elements Concentration and Polycystic Ovary Syndrome (PCOS): Systematic Review and Meta-analysis.Biological trace element research · 2022Pooled it
- The effects of chromium supplementation on blood pressure: a systematic review and meta-analysis of randomized clinical trials.European journal of clinical nutrition · 2022Pooled it
- Kolaviron offers significant neuroprotection on potassium dichromate-induced neurobehavioral, biochemical, histopathological, and immunohistochemical changes in rats.IBRO neuroscience reports · 2026Article
- Ultrasensitive Cr(VI) sensing via HAnalytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2026Article
- Chromium(III) Beyond Insulin: A Mechanistic Roadmap Across the Energy-Redox-Inflammation Triad in Obesity and Cardiometabolic Disease.Biological trace element research · 2026Review
- Capillary Electrophoresis and Atomic Absorption Spectrometry-A Rare Yet Valuable Liaison, Also from a Pharmaceutical Perspective.Molecules (Basel, Switzerland) · 2026Review
- Influence of e-Liquid pH on Heavy Metal Emissions in Open-System Electronic Cigarette Aerosols and Associated Health Risks.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2026Article
- Potassium Dichromate-Impregnated Porous CaO-Derived Eggshells: A Bifunctional Catalyst to Produce Biodiesel.ACS omega · 2026Article
- Foliar spray of salicylic acid and gamma-aminobutyric acid mitigates chromium toxicity in barley by regulating antioxidant defense, nutrient uptake, and secondary metabolites.BMC plant biology · 2026Article
- Valorization of Keratin Waste as a Functional Precursor for PLA/SBS Composite Adsorbent Films.Polymers · 2026Article
- Heavy Metal-Driven Oral Dysbiosis: Salivary Toxicometallomics at the Host-Microbiome Interface Across Pathologies.Life (Basel, Switzerland) · 2026Review
- Designing green-emissive Cu,N-codoped carbon dots by pyrolysis of aromatic precursors and application in sensing of Fe(iii) and Cr(vi).RSC advances · 2026Article
- The Dual Nature of Metals: Essential Nutrients and Environmental Contaminants.International journal of molecular sciences · 2026Review
- Vitamin C modulates Cr(VI)-induced parallel disruptions along the microbiota-gut-brain axis in adult zebrafish: insights from transcriptomic and microbiome analysis.Fish physiology and biochemistry · 2026Article
- Particulate Hexavalent Chromium Inhibits RAD51 Paralogs Necessary for RAD51 Filament Formation and Stabilization During Homologous Recombination Repair.Occupational Health · 2026Article
- Genomic and structural elucidation of multi-heavy metal tolerance in the p-nitrophenol-degrading bacterium Pseudomonas asiatica strain PNPG3.Scientific reports · 2026Article
- In Situ Accelerated Carbon Mineralization for Synergistic Immobilization and Recovery of Hexavalent Chromium Oxyanions from Coal Ash Leachates.ACS omega · 2026Article
- Highly efficient Cr(vi) removal from water using deep eutectic solvents: a sustainable and comprehensive approach.RSC advances · 2026Article
- Evaluation of treatment for acute hexavalent chromium poisoning in human renal proximal tubular epithelial cells with 2,3-dimercapto-1-propanesulfonic acid (DMPS).American journal of translational research · 2026Article
37 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Chromium is a pervasive environmental contaminant that is of great importance because of its toxicity. Hexavalent chromium is a classified group 1 carcinogen with multiple complex mechanisms by which it triggers cancer development. Increased levels of oxidative stress, chromosome breaks, and DNA-adduct formation are some of the major mechanisms by which C(VI) causes cellular damage. Trivalent chromium is another species of chromium that is described as a non-essential metal, and is used in nutritional supplementation. Evidence on nutritional benefit is conflicting which could suggest that humans absorb enough Cr(III) from diet alone, and that extra supplementation is not necessary. This review highlights the differences between Cr(VI) and Cr(III) from a chemical and toxicological perspective, describes short-comings in nutritional research of Cr(III), and explains the multiple mechanisms by which Cr(VI) is involved in the process of carcinogenesis.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.