Evidence map›Paper›PMID 31511643›Full record

ArticleCellular & molecular immunology2020

REGγ controls Th17 cell differentiation and autoimmune inflammation by regulating dendritic cells.

Lei Zhou, Liangfang Yao, Qing Zhang, Wei Xie, Xiaoshuang Wang, Huihui Zhang, Jinjin Xu, Qingxia Lin, Qing Li, Yang Xuan and 11 more

Open access · bronzeAbstract read
In one paragraph

Article in Cellular & molecular immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 28 citations in OpenAlex.

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  12. Reciprocal REGOxidative medicine and cellular longevity · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 3 institutions in 2 countries.

Lei Zhou *Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences, School of Life Sciences, East China Normal University, 500 Dongchuan Road, 200241, Shanghai, P. R. China.
Liangfang Yao *Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences, School of Life Sciences, East China Normal University, 500 Dongchuan Road, 200241, Shanghai, P. R. China.
Qing Zhang *Department of Hematology, Guangdong Second Provincial General Hospital, Guangzhou, Guangdong Province, P. R. China.
Wei XieShanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences, School of Life Sciences, East China Normal University, 500 Dongchuan Road, 200241, Shanghai, P. R. China.
Xiaoshuang WangShanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences, School of Life Sciences, East China Normal University, 500 Dongchuan Road, 200241, Shanghai, P. R. China.
Huihui ZhangShanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences, School of Life Sciences, East China Normal University, 500 Dongchuan Road, 200241, Shanghai, P. R. China.
Jinjin XuShanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences, School of Life Sciences, East China Normal University, 500 Dongchuan Road, 200241, Shanghai, P. R. China.
Qingxia LinShanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences, School of Life Sciences, East China Normal University, 500 Dongchuan Road, 200241, Shanghai, P. R. China.
Qing LiShanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences, School of Life Sciences, East China Normal University, 500 Dongchuan Road, 200241, Shanghai, P. R. China.
Yang XuanShanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences, School of Life Sciences, East China Normal University, 500 Dongchuan Road, 200241, Shanghai, P. R. China.
Lei JiShanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences, School of Life Sciences, East China Normal University, 500 Dongchuan Road, 200241, Shanghai, P. R. China.
Lu WangShanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences, School of Life Sciences, East China Normal University, 500 Dongchuan Road, 200241, Shanghai, P. R. China.
Weicang WangShanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences, School of Life Sciences, East China Normal University, 500 Dongchuan Road, 200241, Shanghai, P. R. China.ORCID http://orcid.org/0000-0002-2722-507X
Weichao WangShanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences, School of Life Sciences, East China Normal University, 500 Dongchuan Road, 200241, Shanghai, P. R. China.
Tingting ShiShanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences, School of Life Sciences, East China Normal University, 500 Dongchuan Road, 200241, Shanghai, P. R. China.
Lei FangShanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences, School of Life Sciences, East China Normal University, 500 Dongchuan Road, 200241, Shanghai, P. R. China.
Biao ZhengShanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences, School of Life Sciences, East China Normal University, 500 Dongchuan Road, 200241, Shanghai, P. R. China.
Lei LiShanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences, School of Life Sciences, East China Normal University, 500 Dongchuan Road, 200241, Shanghai, P. R. China. lli@bio.ecnu.edu.cn.
Shuang LiuDepartment of Hematology, Guangdong Second Provincial General Hospital, Guangzhou, Guangdong Province, P. R. China. liush@gd2h.org.cn.
Bianhong ZhangShanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences, School of Life Sciences, East China Normal University, 500 Dongchuan Road, 200241, Shanghai, P. R. China. bhzhang@bio.ecnu.edu.cn.
Xiaotao LiShanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences, School of Life Sciences, East China Normal University, 500 Dongchuan Road, 200241, Shanghai, P. R. China. xiaotaol@bcm.edu.
East China Normal University · CNGuangdong Provincial People's Hospital · CNBaylor College of Medicine · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Interleukin-17A (IL-17A)-producing helper T (Th17) cells are a subset of CD4

Indexed as

AutoimmunityCell DifferentiationAnimalsAutoantigensCell PolarityDendritic CellsDisease ProgressionEncephalomyelitis, Autoimmune, ExperimentalInflammationInterferon Regulatory Factor-8Interferon Regulatory FactorsInterleukin-6Mice, Inbred C57BLModels, BiologicalProteasome Endopeptidase ComplexTh17 CellsAutoantigensInterferon Regulatory Factor-8Interferon Regulatory FactorsInterleukin-6Ki antigenProteasome Endopeptidase ComplexTransforming Growth Factor beta1DCEAEREGγTGF-βTh17

Identifiers

PMID31511643
PMCPMC7784850
OpenAlexW2972854261

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.