ArticleScientific reports2019
Metabolomic and gene expression approaches reveal the developmental and environmental regulation of the secondary metabolism of yacón (Smallanthus sonchifolius, Asteraceae).
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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20 citing papers in PubMed.
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- DEFGermplasm: a comprehensive digital platform for forest genomic and phenotype data integration.Forestry research · 2025Article
- Discrimination of Radix Astragali from Different Growth Patterns, Origins, Species, and Growth Years by an HMolecules (Basel, Switzerland) · 2023Article
- Phenological and Environmental Factors' Impact on Secondary Metabolites in Medicinal PlantPlants (Basel, Switzerland) · 2023Article
- Responses of Aroma Related Metabolic Attributes ofPlants (Basel, Switzerland) · 2023Article
- Metabolic profiles of Sri Lankan cassava mosaic virus-infected and healthy cassava (Manihot esculenta Crantz) cultivars with tolerance and susceptibility phenotypes.BMC plant biology · 2023Article
- Quantification of Enhydrin and Uvedalin in the Ethanolic Extract ofMolecules (Basel, Switzerland) · 2023Article
- Trends in Phenolic Profiles ofPlants (Basel, Switzerland) · 2023Article
- Distribution Patterns of Essential Oil Terpenes in Native and InvasivePlants (Basel, Switzerland) · 2022Article
- Chemical Diversity of Flavan-3-Ols in Grape Seeds: Modulating Factors and Quality Requirements.Plants (Basel, Switzerland) · 2022Review
- Distribution of Phenolic Compounds and Antioxidant Activity in Plant Parts and Populations of Seven Underutilized WildPlants (Basel, Switzerland) · 2022Article
- Review
- The Diversity of Volatile Compounds in Australia's Semi-Desert GenusPlants (Basel, Switzerland) · 2021Article
- Effect of the Andean Geography and Climate on the Specialized Metabolism of Its Vegetation: The Subtribe Espeletiinae (Asteraceae) as a Case Example.Metabolites · 2021Article
- Article
- Feature-Based Molecular Networking to Target the Isolation of New Caffeic Acid Esters from Yacon (Metabolites · 2020Article
- Essential Oils and Their Main Chemical Components: The Past 20 Years of Preclinical Studies in Melanoma.Cancers · 2020Review
- Metabolomic and Gene Expression Studies Reveal the Diversity, Distribution and Spatial Regulation of the Specialized Metabolism of Yacón (International journal of molecular sciences · 2020Article
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5 authors.
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Abstract
Acting as chemical defense or signaling compounds, secondary metabolites (SMs) play an essential role in the evolutionary success of many angiosperm plant families. However, the adaptive advantages that SMs confer, and the influence of environmental and developmental factors on SMs expression, remains poorly understood. A study of taxa endemic to the variable Andean climate, using a metabolomics approach, may provide further insight. By analyzing gene expression patterns and metabolic fingerprints, we report herein the developmental and environmental regulation of the secondary metabolism of Smallanthus sonchifolius (yacón), a medicinal Andean plant. Our results demonstrate a clear developmental stage dependent regulation of the secondary metabolism of yacón leaves wherein the metabolic diversity increases with plant age. However, environmental factors seem to regulate biosynthetic pathways, creating differences in the expression of chemical classes, pointing to an association between transcription levels of relevant genes and the relative amounts of more than 40 different metabolites. This study suggests that the secondary metabolism of yacón is regulated by a complex interplay between environmental factors and developmental stage and provides insight into the regulatory factors and adaptive roles of SMs in Andean taxa.
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