Evidence map›Paper›PMID 31511371›Full record

ArticlemSphere2019

Global Transcriptomic Analysis of the Candida albicans Response to Treatment with a Novel Inhibitor of Filamentation.

Jesus A Romo, Hao Zhang, Hong Cai, David Kadosh, Julia R Koehler, Stephen P Saville, Yufeng Wang, Jose L Lopez-Ribot

Open access · goldAbstract read
In one paragraph

Article in mSphere, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Antifungal therapy ofBiofilm · 2023
    Article
  3. Imaging-Based Screening Identifies Modulators of theAntimicrobial agents and chemotherapy · 2023
    Article
  4. Imaging-based screening identifies modulators of thebioRxiv : the preprint server for biology · 2023
    Article
  5. Article
  6. Biofilm Alterations on the Stepwise Acquisition of Fluconazole-resistantInternational journal of dermatology and venereology · 2022
    Article
  7. Article
  8. Mechanistic Understanding ofFrontiers in microbiology · 2021
    Review
  9. Review
  10. The Role of Secretory Pathways inJournal of fungi (Basel, Switzerland) · 2020
    Review
  11. Oral Candidiasis: A Disease of Opportunity.Journal of fungi (Basel, Switzerland) · 2020
    Review
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Jesus A RomoDepartment of Biology, The University of Texas at San Antonio, San Antonio, Texas, USA.
Hao ZhangDepartment of Biology, The University of Texas at San Antonio, San Antonio, Texas, USA.
Hong CaiDepartment of Biology, The University of Texas at San Antonio, San Antonio, Texas, USA.
David KadoshDepartment of Microbiology, Immunology and Molecular Genetics, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.ORCID 0000-0001-7237-8481
Julia R KoehlerDivision of Infectious Diseases, Boston Children's Hospital/Harvard Medical School, Boston, Massachusetts, USA.
Stephen P SavilleDepartment of Biology, The University of Texas at San Antonio, San Antonio, Texas, USA.
Yufeng WangDepartment of Biology, The University of Texas at San Antonio, San Antonio, Texas, USA Yufeng.wang@utsa.edu jose.lopezribot@utsa.edu.
Jose L Lopez-RibotDepartment of Biology, The University of Texas at San Antonio, San Antonio, Texas, USA Yufeng.wang@utsa.edu jose.lopezribot@utsa.edu.
Texas Center for Infectious Disease · USBoston Children's Hospital · USThe University of Texas Health Science Center at San Antonio · US

Funding

TISSUE CULTURE---COREP30CA054174 · NCI · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI Robin Jean Leach · 1991 to 2026
$59.1M
UTSA RISE Research Training ProgramR25GM060655 · NIGMS · UNIVERSITY OF TEXAS SAN ANTONIO · PI BAREA-RODRIGUEZ, EDWIN J · 2000 to 2022
$21.6M
Translational Control of Morphology and Virulence in Candida albicansR01AI127692 · NIAID · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI KADOSH, DAVID · 2018 to 2022
$1.9M
Development of novel chemical series of Candida albicans biofilm inhibitorsR01AI119554 · NIAID · UNIVERSITY OF TEXAS SAN ANTONIO · PI LOPEZ-RIBOT, JOSE L., MCHARDY, STANTON FURST · 2015 to 2019
$1.8M
Systems Biology of Plasmodium falciparum: Building and Exploring Network ModelsSC1GM100806 · NIGMS · UNIVERSITY OF TEXAS SAN ANTONIO · PI WANG, YUFENG · 2012 to 2015
$1.5M
Regulation of Protein Synthesis During the C. albicans-Macrophage InteractionR21AI142560 · NIAID · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI KADOSH, DAVID · 2019 to 2020
$435k
NCI NIH HHS P30 CA054174NIAID NIH HHS R01 AI119554NIAID NIH HHS R01 AI127692NIAID NIH HHS R21 AI142560NIGMS NIH HHS R25 GM060655NIGMS NIH HHS SC1 GM100806
6 · The paper itself

Abstract

The opportunistic pathogenic fungus

Indexed as

Gene Expression ProfilingAntifungal AgentsBiofilmsCandida albicansDown-RegulationGene Expression Regulation, FungalGenome, FungalHyphaeUp-RegulationVirulenceVirulence FactorsAntifungal AgentsVirulence FactorsantivirulenceCandida albicanscandidiasisfilamentation

Identifiers

PMID31511371
PMCPMC6739497
OpenAlexW2972374249

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.