Evidence map›Paper›PMID 31511324›Full record

ArticleThe Journal of biological chemistry2019

MbnH is a diheme MauG-like protein associated with microbial copper homeostasis.

Grace E Kenney, Laura M K Dassama, Anastasia C Manesis, Matthew O Ross, Siyu Chen, Brian M Hoffman, Amy C Rosenzweig

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Biochemistry · 2025
    Article
  2. Review
  3. Review
  4. Capturing aBiochemistry · 2023
    Article
  5. Copper binding by a unique family of metalloproteins is dependent on kynurenine formation.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Grace E KenneyDepartments of Molecular Biosciences and Chemistry, Northwestern University, Evanston, Illinois 60208.ORCID 0000-0002-9579-3351
Laura M K DassamaDepartments of Molecular Biosciences and Chemistry, Northwestern University, Evanston, Illinois 60208.ORCID 0000-0002-0851-6373
Anastasia C ManesisDepartments of Molecular Biosciences and Chemistry, Northwestern University, Evanston, Illinois 60208.
Matthew O RossDepartments of Molecular Biosciences and Chemistry, Northwestern University, Evanston, Illinois 60208.ORCID 0000-0003-2115-9806
Siyu ChenDepartments of Molecular Biosciences and Chemistry, Northwestern University, Evanston, Illinois 60208.
Brian M HoffmanDepartments of Molecular Biosciences and Chemistry, Northwestern University, Evanston, Illinois 60208.
Amy C RosenzweigDepartments of Molecular Biosciences and Chemistry, Northwestern University, Evanston, Illinois 60208 amyr@northwestern.edu.ORCID 0000-0001-8472-4134
Northwestern University · US

Funding

Metalloenzymes and metal homeostasisR35GM118035 · NIGMS · NORTHWESTERN UNIVERSITY · PI AMY C. ROSENZWEIG · 2016 to 2026
$7.1M
Coboglobins-Cobalt-Substituted Hemoglobins and MyoglobinR01GM111097 · NIGMS · NORTHWESTERN UNIVERSITY · PI HOFFMAN, BRIAN M · 2014 to 2025
$6.7M
Copper Acquisition by Methanotrophs.F32GM110934 · NIGMS · NORTHWESTERN UNIVERSITY · PI DASSAMA, LAURA · 2014 to 2016
$164k
NIGMS NIH HHS F32 GM110934NIGMS NIH HHS R01 GM111097NIGMS NIH HHS R35 GM118035
6 · The paper itself

Abstract

Methanobactins (Mbns) are ribosomally-produced, post-translationally modified peptidic copper-binding natural products produced under conditions of copper limitation. Genes encoding Mbn biosynthetic and transport proteins have been identified in a wide variety of bacteria, indicating a broader role for Mbns in bacterial metal homeostasis. Many of the genes in the Mbn operons have been assigned functions, but two genes usually present,

Indexed as

Amino Acid SequenceBacteriaBacterial ProteinsComputational BiologyCopperHomeostasisImidazolesMethylosinus trichosporiumOligopeptidesOperonProtein Processing, Post-TranslationalBacterial ProteinsCopperImidazolesmethanobactinOligopeptidesbioinformaticscrystal structurediheme cytochrome c peroxidasehemeMauGMbnHmetal homeostasismetalloproteinmethanobactin

Identifiers

PMID31511324
PMCPMC6827288
OpenAlexW2972517546

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.