Evidence map›Paper›PMID 31511321›Full record

ArticleRNA (New York, N.Y.)2019

Iron-induced transferrin receptor-1 mRNA destabilization: A response to "Neither miR-7-5p nor miR-141-3p is a major mediator of iron-responsive transferrin receptor-1 mRNA degradation".

Masaki Miyazawa, Alexander R Bogdan, Kazunori Hashimoto, Yoshiaki Tsuji

Open access · bronzeAbstract readComment
In one paragraph

Article in RNA (New York, N.Y.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Genome-wide analysis of lncRNA stability in human.PLoS computational biology · 2021
    Article
  2. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 2 countries.

Masaki MiyazawaDepartment of Health Management, Tokai University, Hiratsuka, Kanagawa, 259-1292 Japan.
Alexander R BogdanMinnesota Department of Health, St. Paul, Minnesota 55164, USA.
Kazunori HashimotoDepartment of Occupational and Environmental Health, Nagoya University Graduate School of Medicine, Showa-ku, Nagoya, Aichi 466-8550, Japan.
Yoshiaki TsujiDepartment of Biological Sciences, Toxicology Program, North Carolina State University, Raleigh, North Carolina 27695, USA.
Minnesota Department of Health · USNagoya University · JPNorth Carolina State University · USTokai University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We read with great interest the Divergent Views article by Connell and colleagues disputing our recent publication describing a role for two microRNAs in the iron-mediated regulation of transferrin receptor 1 (TfR1) mRNA stability. Our publication sought to shed light on a long-standing question in the field of cellular iron metabolism, and we welcome commentary and critique. However, there are several critical issues contained in the article by Connell and colleagues that require further consideration. We appreciate the opportunity to reply here.

Indexed as

IronMicroRNAsReceptors, TransferrinRNA, MessengerRNA StabilityIronMicroRNAsReceptors, TransferrinRNA, Messenger

Identifiers

PMID31511321
PMCPMC6795137
OpenAlexW2972718787

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.